Figure 1

Adjusted geometric mean salivary cortisol concentrations as a function of time since waking according to 2nd trimester blood Pb quintile ¹ . 1-Smoothed function was derived by modeling the time since waking as a restricted cubic polynomial spline with 918 women’s salivary cortisol concentrations as the outcome. Only samples collected in the correct time windows are included in this plot. The model was adjusted for maternal age (continuous years), education (continuous years), body mass index (continuous), marital status (married, free union, or single/separated/divorced), gestational age at time of cortisol collection (continuous weeks), parity (1, 2, 3, or 4+), and maternal smoking status during pregnancy (never, former, or current).