Skip to main content

Table 3 Adjusted change in cortisol AM rise according to blood, tibia, and patella Pb concentrations in Mexico City women (2007–2011) 1

From: Relationships between lead biomarkers and diurnal salivary cortisol indices in pregnant women from Mexico City: a cross-sectional study

Pb biomarker/quantile % Change in cortisol per hour (95% CI) β Coefficient (95% CI)
Blood Pb (n = 873) 2   
Quintile 1 (0- < 1.8 µg/dL) 5 (−5, 16) Ref
Quintile 2 (1.8- < 2.4 µg/dL) 5 (−5, 16) 0.00 (−0.06, 0.06)
Quintile 3 (2.4- < 3.4 µg/dL) 7 (−4, 18) 0.01 (−0.05, 0.07)
Quintile 4 (3.4- < 5.1 µg/dL) −5 (−14, 5) −0.04 (−0.11, 0.02)
Quintile 5 (≥5.1 µg/dL) −8 (−16, 2) −0.06 (−0.12, 0.00)
Continuous, per 2.5 µg/dL N/A −0.02 (−0.04, 0.00)
Tibia Pb (n = 575) 3   
Quantile 1 (<2 µg/g) 4 (−4, 12) Ref
Quantile 2 (2- < 4.3 µg/g) −8 (−21, 7) −0.05 (−0.12, 0.03)
Quantile 3 (4.3- < 6.7 µg/g) 7 (−7, 23) 0.02 (−0.05, 0.09)
Quantile 4 (6.7- < 11.1 µg/g) −9 (−22, 5) −0.05 (−0.12, 0.02)
Quantile 5 (≥11.1 µg/g) 8 (−7, 25) 0.02 (−0.05, 0.09)
Patella Pb (n = 568) 3   
Quantile 1 (<2 µg/g) 2 (−6, 10) Ref
Quantile 2 (2- < 4.5 µg/g) 11 (−3, 27) 0.04 (−0.03, 0.11)
Quantile 3 (4.5- < 7.8 µg/g) −11 (−22, 3) −0.05 (−0.12, 0.02)
Quantile 4 (7.8- < 12.7 µg/g) −2 (−15, 12) −0.01 (−0.08, 0.06)
Quantile 5 (>12.7-43.2 µg/g) 7 (−7, 23) 0.03 (−0.04, 0.10)
  1. 1-Only includes women who collected their first and second cortisol samples in the correct time window.
  2. 2-Salivary cortisol concentrations are modeled as a function of time since waking, Pb biomarker, a Pb biomarker x time interaction term, and covariates.
  3. 3-Adjusted for above covariates and maternal calf circumference at 1-month postpartum.