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Table 4 Incidence of lung tumors and mesotheliomas in rats following exposure to asbestos samples (from [[65],[66]])

From: Quantification of short and long asbestos fibers to assess asbestos exposure: a review of fiber size toxicity

Inhalation 10 mg/m3*
  Amosite
  LAF SAF
11% >10 μm 0.1% > 10 μm
Number of rats 40 42
Lung tumor 11 (27.5%) 0 (0%)
Mesothelioma 3 (7.5%) 1 (2.4%)
  Chrysotile
  LAF SAF
2% >10 μm 0.7% > 10 μm
0.1% >30 μm 0.03% >30 μm
Number of rats 40 40
Lung tumor 20 (50%) 7 (17.5%)
Mesothelioma 3 (7.5%) 1 (2.4%)
Mesotheliomas after intraperitoneal injection**
  Amosite
  LAF SAF
Number of rats Not provided Not provided
10 mg 21 (88%) 0 (0%)
25 mg 20 (90%) 1 (4%)
  Chrysotile
Number of rats 24 24
2.5 mg 22 (91.6%) 8 (33.3%)
25 mg 23 (95.8%) 22 (91.6%)
  1. *Inhalation: 2 lung tumors and no mesothelioma in control rats.
  2. **Intraperitoneal injection: no mesothelioma in control rats.