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Table 3 Standardized Mortality Ratios (SMRs), Underlying cause of death

From: Mortality study of civilian employees exposed to contaminated drinking water at USMC Base Camp Lejeune: a retrospective cohort study

Underlying Cause of Death Camp Pendleton (reference) Camp Lejeune
Obs. Exp. SMR (95% CI) Obs. Exp. SMR (95% CI)
All Causes 869 1,084 0.80 (0.75, 0.86) 654 765 0.86 (0.79, 0.92)
All Cancers 257 322 0.80 (0.70, 0.90) 229 237 0.97 (0.84, 1.10)
Diseases of Primary Interest
Kidney Cancer 6 7.27 0.82 (0.30, 1.80) 7 5.40 1.30 (0.52, 2.67)
Bladder Cancer 4 5.78 0.69 (0.19, 1.77) 2 3.76 0.53 (0.06, 1.92)
Liver* Cancer 11 9.84 1.12 (0.56, 2.00) 3 7.23 0.42 (0.09, 1.21)
Esophageal Cancer 8 8.78 0.91 (0.39, 1.80) 4 6.21 0.64 (0.18, 1.65)
Cervical Cancer 0 2.94 0 (0.00, 1.25) 1 2.98 0.34 (0.01, 1.87)
Hematopoietic Cancers 25 28.83 0.87 (0.56, 1.28) 24 20.89 1.15 (0.74, 1.71)
 Hodgkin Lymphoma 0 0.96 0.00 (0.00, 3.86) 1 0.83 1.20 (0.03, 6.69)
 NHL** 8 11.50 0.70 (0.30, 1.37) 5 8.34 0.60 (0.19, 1.40)
 Multiple Myeloma 3 5.81 0.52 (0.11, 1.51) 6 3.99 1.50 (0.55, 3.28)
 Leukemias 14 10.56 1.33 (0.72, 2.22) 12 7.73 1.55 (0.80, 2.71)
Diseases of Secondary Interest
Pancreatic Cancer 22 16.39 1.34 (0.84, 2.03) 12 11.77 1.02 (0.53, 1.78)
Colon Cancer 13 25.32 0.51 (0.27, 0.88) 12 17.61 0.68 (0.35, 1.19)
Rectal Cancer 4 5.07 0.79 (0.22, 2.02) 4 3.76 1.06 (0.29, 2.72)
Soft Tissue Cancers 2 2.10 0.95 (0.12, 3.44) 1 1.75 0.57 (0.01, 3.19)
Brain Cancer 9 7.94 1.13 (0.52, 2.15) 7 6.68 1.05 (0.42, 2.16)
Laryngeal Cancer 1 3.09 0.32 (0.01, 1.80) 4 2.16 1.85 (0.50, 4.74)
Lung*** Cancer 82 101.60 0.81 (0.64, 1.00) 80 73.20 1.09 (0.87, 1.36)
Oral Cancers**** 2 6.15 0.33 (0.04, 1.18) 4 4.43 0.90 (0.25, 2.31)
Breast (female) Cancer 14 23.46 0.60 (0.33, 1.00) 21 21.42 0.98 (0.61, 1.50)
Prostate Cancer 12 15.65 0.77 (0.40, 1.34) 10 9.16 1.09 (0.52, 2.01)
Liver Diseases 19 22.64 0.84 (0.50, 1.31) 9 18.85 0.48 (0.22, 0.91)
Kidney Diseases 7 13.98 0.50 (0.22, 1.00) 7 9.00 0.78 (0.34, 1.54)
ALS 4 2.96 1.35 (0.37, 3.46) 1 2.29 0.44 (0.01, 2.44)
Multiple Sclerosis 1 1.92 0.52 (0.01, 2.91) 1 1.89 0.53 (0.01, 2.95)
Parkinson’s Disease 4 4.54 0.88 (0.24, 2.26) 5 2.28 2.19 (0.71, 5.11)
Smoking-related Diseases (not known to be related to solvent exposure)
Stomach Cancer 7 7.88 0.89 (0.36, 1.83) 4 5.50 0.73 (0.20, 1.86)
Cardiovascular Disease† 317 380.45 0.83 (0.75, 0.93) 210 244.37 0.86 (0.75, 0.98)
COPD 47 47.29 0.99 (0.73, 1.32) 40 29.99 1.33 (0.95, 1.82)
  1. *Biliary passages, liver and gall bladder ** Non-Hodgkin Lymphoma.
  2. ***Trachea, bronchus, and lung ****Buccal cavity and Pharynx.
  3. †Includes diseases of the heart and other diseases of the circulatory system.
  4. Camp Lejeune = 4,647; person-years = 123,659.
  5. Camp Pendleton = 4,690; person-years = 123,065.