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Table 3 Classification of lung injury according to the use of characteristics of humidifier disinfectant

From: Exposure characteristics of familial cases of lung injury associated with the use of humidifier disinfectants

Classification Total Fatal Non-fatal P-value
Use of humidifier disinfectant prior to the onset of 1st lung injury     
Yes 38 (100%) 10 (100%) 28 (100%)   NA
No   0   0   0  
Total months of humidifier use    
<12 15 (37%) 7 (70%) 8 (29%) 0.011
12-24 13 (34%) 3 (30%) 10 (36%)  
30-72 11 (29%)   10 (36%)  
Sleeping in a room with a humidifier using disinfectant
Yes 26 (68%) 7 (70%) 19 (68%) 0.900
No 12 (32%) 3 (30%) 9 (32%)  
Hours of humidifier disinfectant use per day*
<11.5 19 (50%) 5 (50%) 14 (50%) 1.000
> = 11.5 19 (50%) 5 (50%) 14 (50%)  
Duration of humidifier disinfectant use after lung injury symptom onset, months    
<2 14 (37%) 5 (50%) 9 (32%) 0.320
> = 2 24 (63%) 5 (50%) 19 (68%)  
Duration of humidifier disinfectant use before lung injury symptom onset, years     
≤ 1 17 (45%) 7 (70%) 10 (36%) 0.060
1.1-19 21 (55%) 3 (30%) 18 (64%)  
Type of disinfectant     
PHMG 36 (95%) 9 (90%) 27 (96%) 0.462
PHG 2 (5%) 1 (10%) 1 (4%)  
Type of humidifier disinfectant    
Oxy® 26 (68%) 7 (70%) 19 (68%) 0.900
Other six brands 12 (32%) 3 (30%) 9 (32%)  
  1. *Includes time sleeping,
  2. Abbreviations:
  3. PHMG = polyhexamethylene guanidine phosphate.
  4. PGH = oligo(2-(2-ethoxy)ethoxyethyl guanidinium.
  5. NA = not applicable.