Table 2 Exposure to PM 10 , PM 2.5 , and PM 10–2.5 and risk of PD in the Nurses’ Health Study, 1990–2008 (N = 111,769 women at baseline)
From: Particulate matter and risk of parkinson disease in a large prospective study of women
Age adjusted | Multivariatea | ||||||
|---|---|---|---|---|---|---|---|
PY | Cases | RR | 95% CI | RR | 95% CI | P-trend | |
Quartiles of PM 10 | |||||||
3.8-21.0 μg/m3 | 484444 | 141 | 1.00 | Ref | 1.00 | Ref | |
21.0– 24.3 μg/m3 | 484483 | 135 | 1.06 | (0.83, 1.34) | 1.09 | (0.86, 1.39) | |
24.3 – 28.3 μg/m3 | 484520 | 120 | 1.02 | (0.80, 1.30) | 1.03 | (0.80, 1.32) | |
28.3 – 88.3 μg/m3 | 484550 | 112 | 1.03 | (0.80, 1.32) | 1.03 | (0.78, 1.37) | 0.92 |
Continuous^ PM 10 | 1937996 | 508 | 0.99 | (0.86, 1.12) | 0.99 | (0.84, 1.16) | |
Quartiles of PM 2.5 | |||||||
1.2-12.6 μg/m3 | 484429 | 131 | 1.00 | Ref | 1.00 | Ref | |
12.6-15.0 μg/m3 | 484482 | 131 | 1.12 | (0.88, 1.43) | 1.07 | (0.83, 1.38) | |
15.0-17.4 μg/m3 | 484513 | 137 | 1.23 | (0.97, 1.57) | 1.14 | (0.88, 1.48) | |
17.4-73.9 μg/m3 | 484573 | 109 | 1.17 | (0.90, 1.51) | 1.10 | (0.83, 1.45) | 0.43 |
Continuous^ PM 2.5 | 1937996 | 508 | 1.17 | (0.90-1.51) | 1.08 | (0.81-1.45) | |
Quartiles of PM 10–2.5 | |||||||
0-7.2 μg/m3 | 484479 | 149 | 1.00 | (Ref) | 1.00 | (Ref) | |
7.2-9.2 μg/m3 | 484496 | 121 | 0.87 | (0.69, 1.11) | 0.91 | (0.71, 1.16) | |
9.2-12.0 μg/m3 | 484495 | 119 | 0.87 | (0.68, 1.11) | 0.93 | (0.72, 1.20) | |
12.0-67.1 μg/m3 | 484506 | 119 | 0.87 | (0.68, 1.11) | 0.93 | (0.69, 1.26) | 0.64 |
Continuous^ PM 10–25 | 1937996 | 508 | 0.90 | (0.74-1.09) | 0.92 | (0.71-1.19) | |