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Table 4 Exposure to PM 10 , PM 2.5 , and PM 102.5 and risk of PD in the NursesHealth Study among non-movers, 19902008 (N = 80,544 women at baseline who did not move during the study)

From: Particulate matter and risk of parkinson disease in a large prospective study of women

 

Multivariatea

 

PY

Cases

RR

95% CI

P-trend

Quartiles of PM 10

     

 3.8-21.0 μg/m3

395353

123

1.00

Ref

 

 21.0– 24.3 μg/m3

395383

115

1.09

(0.84, 1.41)

 

 24.3 – 28.3 μg/m3

395419

100

1.00

(0.76, 1.33)

 

 28.3 – 88.3 μg/m3

395426

90

0.98

(0.76, 1.33)

0.92

Continuous^ PM 10

1581580

430

0.99

(0.89, 1.09)

 

Quartiles of PM 2.5

     

 1.2-12.6 μg/m3

395343

110

1.00

Ref

 

 12.6-15.0 μg/m3

395383

111

1.10

(0.83, 1.45)

 

 15.0-17.4 μg/m3

395409

121

1.25

(0.94, 1.65)

 

 17.4-73.9 μg/m3

395446

88

1.11

(0.81, 1.52)

0.43

Continuous^ PM 2.5

158446

430

1.08

(0.81-1.45)

 

Quartiles of PM 102.5

     

 0-7.2 μg/m3

395375

132

1.00

(Ref)

 

 7.2-9.2 μg/m3

395394

106

0.93

(0.71, 1.21)

 

 9.2-12.0 μg/m3

395397

96

0.90

(0.68, 1.20)

 

 12.0-67.1 μg/m3

395395

96

0.90

(0.63, 1.28)

0.64

Continuous^ PM 1025

1937996

430

0.95

(0.85-1.05)

 
  1. PY: person years; RR: relative risk; 95% CI: 95 percent confidence interval.
  2. aadjusted for age, smoking, region (northeast, midwest, west, and south), population density, caffeine intake (<100 mg/day vs. over 100 mg/day) and ibuprofen use (ever/never user).
  3. ^per 10 μg/m3.