Methylation coefficients of our (epi)gene hits within the broader MAPK signaling system. A nexus integrating all BioCarta MAP kinase genes to other previously studied MAPK networks is diagramed, wherein nodes representing the genes within the BioCarta MAP kinase pathway (84 total) are outlined and labeled in dark black. Arrows indicate known direction of action. Methylation coefficients (from Table 3) are represented here in a scale from blue (negative values), to white (zero), to orange (positive values). For simplicity, both unmeasured values and zero are represented in white. Exposure-specific MAPK coefficients are shown across all three of our models: (a) black carbon; (b) sulfates; and (c) the multi-pollutant paradigm.