Type of chlorinated solvent | Intensity of exposure risk valuea | Cleft palate cases | Controls | Adjusted odds ratiob | 95% confidence interval | p- value for trend | ||
---|---|---|---|---|---|---|---|---|
n | % | n | % | |||||
Propylene dichloride | 0.00 | 1148 | 98.7 | 240907 | 99.4 | 1.00 | Referent | 0.031 |
0.01-0.02 | 5 | 0.4 | 508 | 0.2 | 1.95 | 0.80, 4.76 | ||
0.03-17.70 | 3 | 0.3 | 506 | 0.2 | 1.03 | 0.33, 3.25 | ||
>17.70 | 7 | 0.6 | 504 | 0.2 | 2.32 | 1.09, 4.95 | ||
Tetrachloroethane | 0.00 | 1146 | 98.5 | 240470 | 99.2 | 1.00 | Referent | 0.010 |
0.01-0.18 | 3 | 0.3 | 653 | 0.3 | 0.90 | 0.29, 2.82 | ||
0.19-1.69 | 4 | 0.3 | 653 | 0.3 | 1.14 | 0.42, 3.08 | ||
>1.69 | 10 | 0.9 | 649 | 0.3 | 2.66 | 1.40, 5.04 | ||
1,1,2-trichloroethane | 0.00 | 1141 | 98.1 | 239864 | 98.9 | 1.00 | Referent | 0.059 |
0.01-0.45 | 8 | 0.7 | 853 | 0.4 | 1.66 | 0.82, 3.37 | ||
0.46-1.78 | 4 | 0.3 | 855 | 0.4 | 0.84 | 0.31, 2.27 | ||
>1.78 | 10 | 0.9 | 853 | 0.4 | 1.99 | 1.05, 3.76 | ||
1,2,3-trichloropropane | 0.00 | 1139 | 97.9 | 239578 | 98.8 | 1.00 | Referent | 0.083 |
0.01-16.45 | 10 | 0.9 | 950 | 0.4 | 1.77 | 0.94, 3.37 | ||
16.46-132.51 | 4 | 0.3 | 947 | 0.4 | 0.74 | 0.28, 2.00 | ||
>132.51 | 10 | 0.9 | 950 | 0.4 | 1.91 | 1.01, 3.63 |