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Table 4 Odds ratio for lung cancer associated with occupational exposure to wood dust, stratified by smoking status, and test for interaction

From: Occupational exposure to wood dust and risk of lung cancer in two population-based case–control studies in Montreal, Canada

  Never-low smokers Medium-heavy smokers p-value
  Controls Cases OR* 95% CI Controls Cases OR* 95% CI (interaction)
Study I Population Controls      Population Controls      
No exposure 162 56 1.0 (ref) 227 574 1.0 (ref)  
Any level of exposure 48 19 0.7 0.3 1.4 96 208 0.7 0.5 1.0 0.714
Non-substantial level 31 15 0.4 0.1 1.2 44 106 0.8 0.5 1.2 0.310
Substantial level 17 4 1.0 0.4 2.8 52 102 0.6 0.4 1.0 0.110
Study I Cancer controls      Cancer controls      
No exposure 411 56 1.0 (ref) 661 574 1.0 (ref)  
Any level of exposure 83 19 0.9 0.4 1.7 194 208 1.2 0.9 1.5 0.508
Non-substantial level 50 7 0.5 0.2 1.3 111 106 1.0 0.8 1.4 0.790
Substantial level 33 12 1.6 0.7 3.9 83 102 1.3 0.9 1.9 0.235
Study II Population Controls      Population Controls      
No exposure 269 40 1.0 (ref) 371 461 1.0 (ref)  
Any level of exposure 87 10 0.8 0.3 1.8 167 225 1.2 0.9 1.6 0.196
Non-substantial level 70 5 0.5 0.2 1.3 131 162 1.1 0.8 1.5 0.078
Substantial level 17 5 2.4 0.7 7.9 36 63 1.6 1.0 1.5 0.805
  1. *adjusted for age, ethnolinguistic group, years of education, median family income, respondent status, cigarette index and IARC Group 1 known carcinogens (asbestos, diesel exhaust, formaldehyde, cadmium, chromium VI, nickel and silica).