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Table 1 Butyrylcholinesterase (BChE) enzyme activity in Gulf War veterans

From: Butyrylcholinesterase genotype and enzyme activity in relation to Gulf War illness: preliminary evidence of gene-exposure interaction from a case–control study of 1991 Gulf War veterans

 

n

BChE mean (SD) activity*

All veterans in study

304

1.10 (0.26)

BChE genotype

  U/U

189

1.19 (0.24)

  U/K

87

1.01 (0.21)

  K/K

13

0.80 (0.15)

  U/AK

10

0.76 (0.18)

  U/A

3

1.03 (0.12)

  A/F

1

0.92

  AK/F

1

0.69

  Common variants combined (U/U and U/K)

276

1.13 (0.24)

  Less common variants combined (K/K, U/AK, U/A, A/F, AK/F)

28

0.81 (0.17)↑

Race

  White

265

1.10 (0.26)

  Black

26

1.07 (0.24)

  Other

8

1.12 (0.23)

Sex

  Male

282

1.11 (0.25)

  Female

22

0.95 (0.26)↑↑

Age at time of study

  29-39

189

1.10 (0.25)

  40-49

77

1.14 (0.27)

  50+

38

1.05 (0.23)

Gulf War illness case status

  Gulf War illness cases

144

1.10 (0.24)

  Gulf War veteran controls

160

1.10 (0.27)

  1. BChE = butyrylcholinesterase, SD = standard deviation.
  2. *Mean enzyme activity expressed in μmoles benzoylcholine hydrolyzed per minute per mL of serum.
  3. ↑Mean enzyme activity differs significantly from U/U and U/K (p < 0.001).
  4. ↑↑Mean enzyme activity differs significantly from males (p = 0.003).
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Environmental Health

ISSN: 1476-069X