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Figure 1 | Environmental Health

Figure 1

From: The effect of oxythioquinox exposure on normal human mammary epithelial cell gene expression: A microarray analysis study

Figure 1

Quantitative analysis of immunofluorescence microscopy. Confocal microscopy analysis of p53 expression. Integrated intensity measures were obtained from Fluoview and graphed with GraphPad Prism (GraphPad Software, San Diego, CA) to determine area under the curve as a measure of comparative p53 protein expression for each treatment time point. Data is shown for each time point per cell strain on the ordinate and the intensity on the abscissa (arbitrary units, AU). There was an increase in p53 protein expression for all of the strains tested in direct correlation with OTQ exposure. In one intermediate strain (3), p53 expression was 10-fold lower at all time points.

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Environmental Health

ISSN: 1476-069X