Dioxin-like activities in serum across European and Inuit populations

Table 3 Multiple regressions of the combined study groups

Response variable	Homogeneity of slope (p value)	Common slope, Estimate (SE), p value	Common intercept (p value)	Adjusted R square
AhRag (n = 327)
CB-153	0.95	-0.03 (0.04), 0.43	0.001	0.05
p,p'-DDE	0.28	-0.02 (0.05), 0.70	0.001	0.05
AhR-TEQ (n = 324)
CB-153	0.54	0.11(0.04), 0.77	< 0.001	0.20
p,p'-DDE	0.99	0.08(0.05), 0.07	< 0.001	0.20
AhRcomp (n = 327)
CB-153	0.01	-*	-*	-*
p,p'-DDE	0.80	-0.03 (0.03), 0.24	< 0.001	0.18

Both AhR activities and POP markers are ln transformed. Homogeneity of slope: test for homogeneity of association between exposure variables and outcome variables across the study group (p > 0.05, accept the hypotheses of homogeneity of slope). Common slope: the estimated common slope across study groups assuming homogeneity (p > 0.05, accept the hypotheses that slope equals to zero). Common intercept: test of a common intercept across study groups assuming a common slope (p > 0.05, accept the hypotheses having common intercept across the study groups). Adjusted R square assumes a common slope. *: Since heterogeneity of slope exists between CB-153 and AhRcomp across the study groups, i.e. there were country differences in the association of CB-153 and AhRcomp, no further evaluation was performed.

ISSN: 1476-069X