Low dose radiation and cancer in A-bomb survivors: latency and non-linear dose-response in the 1950–90 mortality cohort

Table 1 Linear model^a

^a0 – 20 mSv subcohort, Excess Relative Risk ERR = βD_φ with β constrained by 1 + ERR ≥ 0 for all data cells. D_φ is the weighted adjusted colon dose (neutron RBE = 10), lagged by φ years, in 10 mSv units. The control model is nested by β = 0.
^bdeaths in the subcohort from the specified cancer
^cLatency φ_m is chosen in the range 5 – 44 years. to minimise linear model Deviance for the given cancer site and gender. Where italicised, φ_m minimises Dev subject to ERR ≥ 0, equivalent to β ≥ 0
^ddeaths in the subcohort from the specified cancer, for which D_φ > 0 where φ = φ_m
^eThe likelihood ratio test LRT_lin-con compares the fitted linear model with the control model at φ_m and is χ² distributed on 1 degree of freedom
^fERR_1,φ is the Excess Relative Risk at D_φ = 1 with φ = φ_m
^g95% Profile Likelihood Confidence Intervals are calculated with φ fixed at φ_m
^hDeviance of the fitted model
ⁱPearson Chi-Square of the fitted model
^jDegrees of Freedom of the fitted model
^kdifference between Observed (= Expected) cases and the number expected if D_φ is set to 0 in every cell after fitting the model

ISSN: 1476-069X