| |
Stomach
|
Liver
|
Lung
|
|---|
|
gender
|
M/F
|
M/F
|
M/F
|
|
cases
b
|
1482
|
540
|
524
|
|
φ
m
c
|
6.66
|
38.58
|
16.90
|
|
ca D
φ
> 0
d
|
1412
|
172
|
494
|
|
LRT
lin-con
e
|
2.09
|
11.21
|
2.26
|
|
ERR
1,φ
fg
|
0.09 (-0.03, 0.22)
|
0.69 (0.25, 1.26)
|
0.16 (-0.05, 0.42)
|
|
Dev
h
|
1680.64
|
1258.02
|
1052.43
|
|
Chi-sq
i
|
3205.08
|
2389.85
|
2500.37
|
|
df
j
|
2992
|
2992
|
2992
|
|
Excess
k
|
38.13
|
27.17
|
23.20
|
| |
Colon
|
Uterus
|
All solid
|
|
gender
|
M/F
|
F
|
M/F
|
|
cases
b
|
214
|
263
|
4379
|
|
φ
m
c
|
43.91
|
6.12
|
43.86
|
|
ca D
φ
> 0
d
|
33
|
262
|
365
|
|
LRT
lin-con
e
|
0.19
|
0.51
|
5.03
|
|
ERR
1, φ
fg
|
0.17 (-0.44, 1.17)
|
0.10 (-0.16, 0.44)
|
0.26 (0.03, 0.52)
|
|
Dev
h
|
719.80
|
638.46
|
2133.03
|
|
Chi-sq
i
|
3497.50
|
1010.56
|
2769.51
|
|
df
j
|
2992
|
1513
|
2992
|
|
Excess
k
|
1.51
|
8.88
|
25.01
|
-
a0 – 20 mSv subcohort, Excess Relative Risk ERR = βDφ with β constrained by 1 + ERR ≥ 0 for all data cells. Dφ is the weighted adjusted colon dose (neutron RBE = 10), lagged by φ years, in 10 mSv units. The control model is nested by β = 0.
-
bdeaths in the subcohort from the specified cancer
-
cLatency φm is chosen in the range 5 – 44 years. to minimise linear model Deviance for the given cancer site and gender. Where italicised, φm minimises Dev subject to ERR ≥ 0, equivalent to β ≥ 0
-
ddeaths in the subcohort from the specified cancer, for which Dφ > 0 where φ = φm
-
eThe likelihood ratio test LRTlin-con compares the fitted linear model with the control model at φm and is χ2 distributed on 1 degree of freedom
-
fERR1,φ is the Excess Relative Risk at Dφ = 1 with φ = φm
-
g95% Profile Likelihood Confidence Intervals are calculated with φ fixed at φm
-
hDeviance of the fitted model
-
iPearson Chi-Square of the fitted model
-
jDegrees of Freedom of the fitted model
-
kdifference between Observed (= Expected) cases and the number expected if Dφ is set to 0 in every cell after fitting the model
