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Table 5 Comparison with extrapolations from LSS12a

From: Low dose radiation and cancer in A-bomb survivors: latency and non-linear dose-response in the 1950–90 mortality cohort

Site

gen

LSS12 ERR1 b

2-p ERR1,φ c

φm d

trans ERR1,φ e

φm f

Stomach

M/F

0.0024 (0.001, 0.004)

0.46 (0.11, 0.94)

11.89

0.00 (-0.06, 0.16)

11.85

 

M

0.001 (-0.0005, 0.0028)

2.68 (-0.15, 32.45)

6.14

0.00 (-0.21, 0.17)

21.77

 

F

0.0047 (0.0022, 0.0077)

0.80 (0.15, 1.77)

13.67

0.43 (0.00, 0.96)

13.68

Liver

M/F

0.0037 (0.0013, 0.0065)

1.43 (0.48, 2.95)

36.90

0.95 (0.28, 1.99)

36.90

 

M

0.0048 (0.0017, 0.0088)

1.72 (0.40, 4.25)

36.97

1.30 (0.28, 3.10)

36.97

 

F

0.0019 (-0.0011, 0.0062)

1.24 (0.06, 3.60)

36.90

1.09 (0.15, 2.78)

38.55

Lung

M/F

0.0053 (0.0028, 0.0084)

0.88 (0.12, 3.36)

13.60

0.80 (0.19, 1.99)

13.60

 

M

0.0034 (0.0006, 0.0069)

0.78 (-0.11, 4.91)

13.55

0.74 (0.05, 2.40)

13.55

 

F

0.0089 (0.0041, 0.0151)

1.35 (0.07, 4.83)

21.91

1.04 (0.09, 3.28)

21.91

Colon

M/F

0.0065 (0.0023, 0.0121)

0.05 (-0.53, 1.15)

20.28

0.07 (-0.49, 1.71)

43.98

 

M

0.0048 (-0.0002, 0.0127)

0.30 (-0.59, 3.16)

28.63

0.40 (-0.50, 2.72)

28.63

 

F

0.0081 (0.0022, 0.0077)

0.47 (-0.55, 2.96)

41.62

0.29 (-0.78, 2.26)

41.62

Uterus

F

0.0024 (-0.0006, 0.0067)

0.47 (-0.32, 2.12)

26.91

0.000 (-0.23, 1.06)

26.91

Site

gen

LSS12 ERR 0.025 b

2-p ERR 0.025,φ c

φ m d

trans ERR 0.025,φ d

φ m f

Stomach

M/F

0.00006 (0.000025, 0.0001)

0.39 (0.08, 0.86)

11.89

0.08 (-0.11, 0.23)

11.85

 

M

0.001 (-0.0005, 0.0028)

2.43 (-0.23, 31.08)

6.14

0.16 (-0.16, 0.47)

21.77

 

F

0.0047 (0.0022, 0.0077)

0.71 (0.05, 1.62)

13.67

0.30 (0.01, 0.76)

13.68

Liver

M/F

0.000093 (0.000033, 0.00016)

1.10 (0.26, 2.37)

36.90

0.77 (0.18, 1.67)

36.90

 

M

0.00012 (0.000043, 0.00022)

1.30 (0.12, 3.50)

36.97

1.25 (0.25, 3.00)

36.97

 

F

0.000048 (-0.000028, 0.00016)

1.03 (0.04, 2.94)

36.90

0.43 (0.01, 1.46)

38.55

Lung

M/F

0.00013 (0.00007, 0.00021)

0.86 (0.14, 3.34)

13.60

0.79 (0.20, 2.01)

13.60

 

M

0.000085 (0.000015, 0.00014)

0.96 (-0.05, 5.39)

13.55

0.92 (0.12, 2.92)

13.55

 

F

0.00022 (0.0001, 0.00038)

1.12 (0.08, 4.15)

21.91

0.91 (0.10, 2.87)

21.91

Colon

M/F

0.00017 (0.00006, 0.0003)

0.25 (-0.44, 1.46)

20.28

0.58 (-0.25, 1.85)

43.98

 

M

0.00012 (-0.000005, 0.00032)

0.65 (-0.45, 4.34)

28.63

0.72 (-0.30, 3.72)

28.63

 

F

0.0002 (0.000055, 0.00019)

0.94 (-0.21, 3.17)

41.62

0.85 (-0.15, 2.56)

41.62

Uterus

F

0.00006 (-0.000015, 0.00017)

0.66 (-0.10, 2.44)

26.91

0.25 (-0.09, 1.13)

26.91

  1. aLife Span Study Report 12 [4]
  2. bfrom LSS12 Tables AII, AIII and AIV, scaled by the linear assumption ERR1 = ERR per 10 mSv = 0.01(ERR per Sv) and ERR0.025 = 0.00025(ERR per Sv)
  3. cTwo-phase model fitted to 0 – 20 mSv subcohort at optimal latency (see also Table 3 for M/F results)
  4. dOptimal latency for Two-phase model on 0 – 20 mSv subcohort
  5. eTransient model at fitted to 0 – 20 mSv subcohort at optimal latency (see also Table 2 for M/F results)
  6. fOptimal latency for Transient model on 0 – 20 mSv subcohort
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Environmental Health

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