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Table 5 Multivate linear regression analysis of AhRcomp and POPs

From: AhR transcriptional activity in serum of Inuits across Greenlandic districts

  

Nuuk

Sisimiut

Qaanaaq

Tasiilaq

All

Mena

n

β

p

n

β

p

n

β

p

n

β

p

n

β

p

Σ PCB_14

raw1

38

-.11

.52

51

-.13

.36

41

-.07

.68

34

-.18

.31

164

-.24

<.01

 

+age

38

-.16

.47

51

-.03

.87

41

-.001

1.00

34

-.29

.15

164

-.05

.56

 

+n-3/n-62

38

-.24

.37

37

.29

.12

41

.08

.68

34

-.20

.27

150

-.01

.95

 

+age+n-3/n-6

38

-.30

.34

37

.42

.04

41

.11

.61

34

-.29

.15

150

.10

.35

Σ pesticide

raw1

38

-.09

.59

51

-.20

.17

41

-.12

.46

38

-.27

.11

168

-.24

<.01

 

+age

38

-.10

.59

51

-.12

.45

41

-.07

.75

38

-.36

.05

168

-.06

.53

 

+n-3/n-62

38

-.16

.52

37

.22

.27

41

.01

.97

38

-.29

.10

154

-.04

.73

 

+age+n-3/n-6

38

-.16

.52

37

.29

.17

41

.04

.87

38

-.36

.06

154

.07

.49

Σ POP

raw1

38

-.10

.55

51

-.18

.22

41

-.10

.53

34

-.19

.28

164

-.24

<.01

 

+age

38

-.13

.53

51

-.09

.57

41

-.04

.84

34

-.30

.13

164

-.06

.53

 

+n-3/n-62

38

-.20

.43

37

.25

.20

41

.04

.86

34

-.21

.25

150

-.02

.87

 

+age+n-3/n-6

38

-.22

.43

37

.34

.10

41

.07

.76

34

-.30

.13

150

.09

.46

Womenb

               

Σ PCB_14

raw1

44

.08

.60

42

17

.28

34

-.31

.07

43

-.18

.24

163

-.09

.24

 

+age

44

.16

.37

42

.09

.59

34

-.15

.46

43

-.51

.02

163

-.11

.17

 

+n-3/n-62

44

.18

.25

38

.09

.62

34

-.49

.06

43

-.27

.14

159

-.11

.25

 

+age+n-3/n-6

44

.25

.14

38

.07

.71

34

-.33

.25

43

-.56

.02

159

-.13

.21

Σ pesticide

raw1

44

.07

.67

42

.09

.57

34

-.25

.15

44

-.21

.18

164

-.11

.18

 

+age

44

.11

.49

42

.-.001

.995

34

-.07

.72

44

-.55

.01

164

-.13

.13

 

+n-3/n-62

44

.18

.26

38

-.03

.85

34

-.37

.17

44

-.30

.10

160

-.14

.18

 

+age+n-3/n-6

44

.22

.19

38

-.06

.76

34

-.19

.52

44

-.59

.01

160

-.15

.15

Σ POP

raw1

44

.08

.62

42

.12

.45

34

-.27

.12

43

-.195

.21

163

-.10

.21

 

+age

44

.14

.42

42

.03

.85

34

-.10

.64

43

-.54

.01

163

-.12

.15

 

+n-3/n-62

44

.19

.24

38

.01

.97

34

-.42

.12

43

-.29

.12

159

-.13

.21

 

+age+n-3/n-6

44

.24

.15

38

-.02

.94

34

-.24

.42

43

-.59

.01

159

-.14

.17

Men + Womenc

               

Σ PCB_14

raw1

82

-.55

<.01

93

-.05

.64

75

-.14

.22

77

-.22

.06

327

-.24

<.01

 

+age

82

-.35

.02

93

-.07

.58

75

-.04

.76

77

-.39

.01

327

-.19

<.01

 

+n-3/n-62

82

-.39

.01

75

-.06

.66

75

-.07

.62

77

-.27

.03

309

-.21

<.01

 

+age+n-3/n-6

82

-.21

.25

75

-.08

.55

75

-.001

1.00

77

-.41

.01

309

-.18

.02

Σ pesticide

raw1

82

-.53

<.01

93

-.10

.34

75

-.15

.20

82

-.23

.04

332

-.24

<.01

 

+age

82

-.30

.03

93

-.13

.27

75

-.04

.80

82

-.38

.01

332

-.18

<.01

 

+n-3/n-62

82

-.34

.02

75

-.12

.35

75

-.08

.61

82

-.28

.02

314

-.21

.01

 

+age+n-3/n-6

82

-.17

.28

75

-.14

.29

75

.01

.93

82

-.40

<.01

314

-.18

.02

Σ POP

raw1

82

-.54

<.01

93

-.09

.42

75

-.15

.21

77

-.22

.05

327

-.24

<.01

 

+age

82

-.32

.03

93

-.11

.35

75

-.04

.80

77

-.40

.02

327

-.19

<.01

 

+n-3/n-62

82

-.37

.01

75

-.10

.43

75

-.07

.62

77

-.27

.03

309

-.21

<.01

 

+age+n-3/n-6

82

-.19

.28

75

-.13

.35

75

.011

.95

77

-.41

.01

309

-.18

.02

  1. The analyses were performed on ln transformed data with AhRcomp as dependent and POPs as independent variables before and upon adjusted for the potential confounders.
  2. 1: non-adjusted data.
  3. 2: ratio of n-3 to n-6 fatty acids in serum.
  4. a: Combining districts is not allowed according to the multiple regression analyses.
  5. b: Combining districts is allowed according to the multiple regression analyses.
  6. c: Combining districts and sex is not allowed according to the multiple regression analyses.
  7. For Σ PCB_14, Σ pesticide and Σ POP and AhRcomp, see the legend of Table 2 and Table 3.
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ISSN: 1476-069X