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Table 3 Main effects* of arsenic and covariates on logged urinary 8-OHdG (μg/l) (N = 290)

From: GSTM1 and APE1 genotypes affect arsenic-induced oxidative stress: a repeated measures study

  Urine Drinking water Toenail
Variable β 95% CI β 95% CI β 95% CI
Arsenic quartile       
   1st reference   reference   reference  
   2nd 0.16 (-0.15, 0.46) 0.02 (-0.30, 0.34) -0.16 (-0.63, 0.304)
   3rd 0.22 (-0.12, 0.55) 0.22 (-0.11, 0.55) -0.32 (-0.773, 0.13)
   4th 0.17 (-0.21, 0.56) -0.16 (-0.55, 0.23) -0.33 (-0.78, 0.12)
Logged creatinine 2.18 (1.96, 2.40) 2.23 (2.05, 2.42) 2.24 (2.06, 2.42)
BMI -0.01 (-0.06, 0.03) -0.01 (-0.05, 0.03) -0.01 (-0.05, 0.03)
Age 0.01 (0.00, 0.03) 0.02 (0.00, 0.03) 0.01 (0.00, 0.02)
Chews betelnuts -0.40 (-0.78, -0.03) -0.46 (-0.84, -0.09) -0.41 (-0.78, -0.04)
ETS in the home -0.47 (-0.79, -0.16) -0.36 (-0.69,-0.03) -0.43 (-0.75, -0.10)
Education†† -0.72 (-1.10, -0.34) -0.70 (-1.08, -0.32) -0.72 (-1.11, -0.33)
GSTM1 -0.02 (-0.37, 0.33) 0.06 (-0.30, 0.41) -0.01 (-0.36, 0.34)
hOGG1 -0.03 (-0.34, 0.28) -0.01 (-0.32, 0.29) -0.06 (-0.37, 0.24)
APE1 -0.28 (-0.60, 0.04) -0.28 (-0.59, 0.03) -0.40 (-0.73, -0.07)
  1. *Main effects are from three random effects Tobit models.
  2. ETS is environmental tobacco smoke.
  3. ††Education compared secondary or higher to primary or less