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Table 3 Main effects* of arsenic and covariates on logged urinary 8-OHdG (μg/l) (N = 290)

From: GSTM1 and APE1 genotypes affect arsenic-induced oxidative stress: a repeated measures study

 

Urine

Drinking water

Toenail

Variable

β

95% CI

β

95% CI

β

95% CI

Arsenic quartile

      

   1st

reference

 

reference

 

reference

 

   2nd

0.16

(-0.15, 0.46)

0.02

(-0.30, 0.34)

-0.16

(-0.63, 0.304)

   3rd

0.22

(-0.12, 0.55)

0.22

(-0.11, 0.55)

-0.32

(-0.773, 0.13)

   4th

0.17

(-0.21, 0.56)

-0.16

(-0.55, 0.23)

-0.33

(-0.78, 0.12)

Logged creatinine

2.18

(1.96, 2.40)

2.23

(2.05, 2.42)

2.24

(2.06, 2.42)

BMI

-0.01

(-0.06, 0.03)

-0.01

(-0.05, 0.03)

-0.01

(-0.05, 0.03)

Age

0.01

(0.00, 0.03)

0.02

(0.00, 0.03)

0.01

(0.00, 0.02)

Chews betelnuts

-0.40

(-0.78, -0.03)

-0.46

(-0.84, -0.09)

-0.41

(-0.78, -0.04)

ETS† in the home

-0.47

(-0.79, -0.16)

-0.36

(-0.69,-0.03)

-0.43

(-0.75, -0.10)

Education††

-0.72

(-1.10, -0.34)

-0.70

(-1.08, -0.32)

-0.72

(-1.11, -0.33)

GSTM1

-0.02

(-0.37, 0.33)

0.06

(-0.30, 0.41)

-0.01

(-0.36, 0.34)

hOGG1

-0.03

(-0.34, 0.28)

-0.01

(-0.32, 0.29)

-0.06

(-0.37, 0.24)

APE1

-0.28

(-0.60, 0.04)

-0.28

(-0.59, 0.03)

-0.40

(-0.73, -0.07)

  1. *Main effects are from three random effects Tobit models.
  2. †ETS is environmental tobacco smoke.
  3. ††Education compared secondary or higher to primary or less