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Table 2 Crude and Adjusted Odds Ratios and 95% CIs for Skin Lesions Predicted by GST Polymorphisms.

From: A case-control study of GST polymorphisms and arsenic related skin lesions

 

Drinking Water Arsenic Concentrations

 

Crude Model 1

Adjusted Model 1

Genotype

OR (95% CI)

p-value

OR (95% CI)

p-value

GSTP1

    

AA

1.0

 

1.0

 

AG

0.90 (0.69–1.17)

0.44

0.89 (0.68–1.17)

0.41

GG

1.79 (1.12–2.88)

0.02

1.86 (1.15–3.00)

0.01

GSTT1 null

1.0

 

1.0

 

GSTT1 wildtype

1.52 (1.08–2.13)

0.02

1.56 (1.10–2.19)

0.01

GSTM1 null

1.0

 

1.0

 

GSTM1 wildtype

1.0 (0.78–1.29)

0.98

0.99 (0.77–1.28)

0.95

  1. Crude Models adjusted for As concentration of well or As concentration of well water. Model 1 adjusted for L/day of water, well As concentration, age, gender, education, BMI, chewing tobacco, betel nut use, and smoking status