Metals and kidney markers in adult offspring of endemic nephropathy patients and controls: a two-year follow-up study

Table 3 Clinical markers of kidney function in two consecutive investigations

	Variable	N	Median	5%-value	95%-value	Spearman correlation coefficient (p)	ICC	ICC 5%-value
Total protein in urine (mg/L)	2003/04	201	30.0	10	140	-0.03 (p = 0.73)	0.03	-0.09
	2004/05	189	13.5	0	86
Albumin in urine (mg/L)	2003/04	201	5.9	0.9	36	0.05 (0.53)	-0.14	-0.26
	2004/05	188	1.0	0.9	17
β₂-micro-globulin in urine (ng/mL)	2003/04	201	25.1	7.3	171	0.41 (< 0.0001)	-086	-0.89
	2004/05	189	37.5	12.5	244
Creatinine in 1-hour urine (g/L)	2003/04	188	0.27	0.06	1.23	0.29 (p < 0.001)	0.23	0.11
	2004/05	189	0.44	0.11	1.7
Creatinine in 4-hour urine (g/l)	2003/04	201	0.19	0.05	1.43	0.05 (0.47)	-0.04	-0.16
	2004/05	189	0.13	0.03	0.54
Glomerular filtration rate/BSA^#	2003/04	200	59.8	22.4	292	0.07 (0.33)	-0.16	-0.27
	2004/05	189	41.5	5.6	144
CCR (Cockcroft & Gault)/BSA^# (mL/min/m²)	2003/04	199	58.2	41.6	79.7	0.264 (< 0.0003)	0.24	0.12
	2004/05	189	54.4	38.4	87.0
Kidney length (average of both) (mm)	2003/04	201	118.5	106	128.5	0.91 (< 0.0001)	0.92	0.9
	2004/05	189	118	106.5	129.5
Minimal kidney cortex width (average) (mm)	2003/04	201	16.0	12	18.5	0.68 (< 0.0001)	0.66	0.58
	2004/05	189	15.5	12	19

ISSN: 1476-069X