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Table 1 Characteristics of the study subjectsa.

From: Influence of genetic factors on toluene diisocyanate-related symptoms: evidence from a cross-sectional study

  

Exposed workers

Non-exposed workers

  

N

%

N

%

Sexb**

Male/Female

107/25

81/19

55/59

48/52

Smoker

No+Former/Yes

77/52

60/40

71/42

63/37

Atopy

Negative/Positive

94/37

72/28

82/31

73/27

SYMPTOMS

     

Eye symptomsb**

No/Yes

71/57

55/45

89/25

78/22

Wheeze etc.

No/Yes

88/41

68/32

90/24

79/21

Dry coughb**

No/Yes

88/39

69/31

101/13

89/11

Cough with mucus

No/Yes

84/44

66/34

87/27

76/24

Nose bleedb**

No/Yes

96/28

78/23

107/7

94/6

GENOTYPES/PHENOTYPES

     

GSTM1

+/-

65/67

49/51

65/49

57/43

GSTT1

+/-

110/22

83/17

97/17

85/15

GSTM3

AA/AB/BB

94/36/2

71/27/2

78/31/5

68/27/4

GSTP1* 105

II/IV/VV

68/51/13

52/39/10

57/46/11

50/40/10

GSTP1* 114

AA/AV

114/18

86/14

103/11

90/10

GSTP1* 105 +114

A/B/C

68/46/18

51/35/14

57/46/11

50/40/10

NAT1 phenotype

S/IM/R

3/88/41

2/67/31

3/76/35

3/67/30

NAT2 phenotype

S/IM/R

89/33/10

67/25/8

73/38/3

64/33/3

MPO b**

GG/GA/AA

97/29/6

73/22/5

74/40/0

65/35/0

SULT1A1

GG/GA/AA

43/77/12

33/58/9

46/54/14

40/47/12

CYP1A1*2A

A/B/C

116/14/2

88/11/2

97/16/1

85/14/1

CYP1A1*2B

AA/AG/GG

126/5/1

95/4/1

107/7/0

94/6/0

TNF-308

GG/GA/AA

83/35/4

68/29/3

69/35/5

63/32/5

TNF-863

CC/CA/AA

93/28/6

73/22/5

78/32/2

70/29/2

CCL5

GG/GA/AA

84/38/5

66/30/4

72/36/4

64/32/4

HLA-DQB1*05

-/+

88/39

69/31

87/25

78/22

HLA-DQB1*0501b*

-/+

98/29

77/23

98/14

88/12

HLA-DQB1*0502

-/+

118/9

93/7

105/7

94/6

HLA-DQB1*0503

-/+

125/2

98/2

108/4

96/4

HLA-DQB1*0504

-/+

126/1

99/1

112/0

100/0

  1. aData was incomplete for some individuals studied, but these study subjects were included in the analyses when possible. Due to variations in success rate of the genotype analyses, the number of analyzed individuals differs to some extent between the different polymorphisms. Moreover, all 246 individuals approved analysis of metabolizing genes, whereas 239 individuals approved analysis of immune-related genes.
  2. bStatistically significant differences between exposed and non-exposed workers.
  3. *p < 0.05, **p < 0.01.