(1). Laboratory examination |
Blood concentrations of PCB- and dioxin-related compounds |
Total PCB, Peak 1, Peak 2, Peak 3, PCB pattern, CB ratio, Total PCQ, Dioxin-related compounds |
Urinalysis (Protein, Sugar, Occult blood, Urobilinogen, pH) |
Hematological examination |
ESR (1-hour), ESR (2-hour), WBC, RBC, Hb, Ht, MCV, MCH, MCHC, PLT |
Blood chemistry |
T-Bil, D-Bil, GOT, GPT, TP, Alb, albumin/globulin(A/G) ratio, ZTT, TTT, ALP, LAP, γ-GTP, ChE, LDH, |
CPK, TC, HDL-chol, TG, β-lip, BUN, Cre, Na, K, Ca, P, Amy, blood sugar level |
Immunological examination (HBs antigen, α-fetoprotein) |
(2). Interview and physical examination |
Life history (Alcohol, Smoking) |
Chief complaint |
Past history(Before the incident, After the incident) |
Subjective symptoms |
General fatigue, Headache, Cough, Sputum, Abdominal pain, Diarrhea, Constipation |
Numbness, Arthralgia, menstruation disorders |
Physical examination |
Body height, Body weight, Heart rate, Blood pressure, Nutrition, Heart sounds, Respiratory sounds, |
Chest radiography, ECG, Abdominal ultrasonography, |
Hepatomegaly, Splenomegaly, Edema, Lymphadenopathy, Tendon reflex, Sensory examination, |
(3). Dermatological examination |
Interview |
Recent tendency to purulent skin eruptions, Recent recurrence of cystic lesions, |
Past history of acneform eruptions, Past history of pigmentation, |
Physical examination (severity and sites) |
Black comedones, Acneform eruptions, Scar formation, Pigmentation, Nail deformity, |
(4). Dental examination |
Chief complaint |
Toothache, Gingival bleeding, Pus discharge, Gingival swelling, Feeling of tooth extrusion, Pigmentation |
Items for oral examination (No/Yes, site) |
Gingivitis, Marginal periodontitis, Retarded eruptions of permanent teeth, |
Tooth pigmentation, Odontogenesis imperfecta, Abnormal occlusion, Other findings, |
Mucosal pigmentation (severity, site, *pattern, **color) |
Upper gingivae, Lower gingivae, Rt. buccal mucosa, Lt. buccal mucosa, Palate, |
Upper lip, Lower lip |
Teeth radiograph (No/Yes) |
*Selection items for pattern (Diffuse, Spotted, Band-like, Linear, Faint, Scattered) |
**Selection items for color (Black, Brownish, Dark-brownish) |
(5). Ophthalmological examination |
Subjective symptoms (Abnormal discharge from the eyes) |
Objective symptoms |
Edema of the eyelid, Conjunctival pigmentation, Cysts of meibomian glands, |
Cheesy secretion from meibomian glands, |