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Table 2 Annual medical check examination sheet of Yusho patients

From: Association of clinical findings in Yusho patients with serum concentrations of polychlorinated biphenyls, polychlorinated quarterphenyls and 2,3,4,7,8-pentachlorodibenzofuran more than 30 years after the poisoning event

(1). Laboratory examination
Blood concentrations of PCB- and dioxin-related compounds
   Total PCB, Peak 1, Peak 2, Peak 3, PCB pattern, CB ratio, Total PCQ, Dioxin-related compounds
   Urinalysis (Protein, Sugar, Occult blood, Urobilinogen, pH)
Hematological examination
   ESR (1-hour), ESR (2-hour), WBC, RBC, Hb, Ht, MCV, MCH, MCHC, PLT
Blood chemistry
   T-Bil, D-Bil, GOT, GPT, TP, Alb, albumin/globulin(A/G) ratio, ZTT, TTT, ALP, LAP, γ-GTP, ChE, LDH,
   CPK, TC, HDL-chol, TG, β-lip, BUN, Cre, Na, K, Ca, P, Amy, blood sugar level
Immunological examination (HBs antigen, α-fetoprotein)
(2). Interview and physical examination
Life history (Alcohol, Smoking)
Chief complaint
Past history(Before the incident, After the incident)
Subjective symptoms
   General fatigue, Headache, Cough, Sputum, Abdominal pain, Diarrhea, Constipation
   Numbness, Arthralgia, menstruation disorders
Physical examination
   Body height, Body weight, Heart rate, Blood pressure, Nutrition, Heart sounds, Respiratory sounds,
   Chest radiography, ECG, Abdominal ultrasonography,
   Hepatomegaly, Splenomegaly, Edema, Lymphadenopathy, Tendon reflex, Sensory examination,
(3). Dermatological examination
   Recent tendency to purulent skin eruptions, Recent recurrence of cystic lesions,
   Past history of acneform eruptions, Past history of pigmentation,
Physical examination (severity and sites)
   Black comedones, Acneform eruptions, Scar formation, Pigmentation, Nail deformity,
(4). Dental examination
Chief complaint
   Toothache, Gingival bleeding, Pus discharge, Gingival swelling, Feeling of tooth extrusion, Pigmentation
Items for oral examination (No/Yes, site)
   Gingivitis, Marginal periodontitis, Retarded eruptions of permanent teeth,
   Tooth pigmentation, Odontogenesis imperfecta, Abnormal occlusion, Other findings,
Mucosal pigmentation (severity, site, *pattern, **color)
   Upper gingivae, Lower gingivae, Rt. buccal mucosa, Lt. buccal mucosa, Palate,
   Upper lip, Lower lip
Teeth radiograph (No/Yes)
   *Selection items for pattern (Diffuse, Spotted, Band-like, Linear, Faint, Scattered)
   **Selection items for color (Black, Brownish, Dark-brownish)
(5). Ophthalmological examination
Subjective symptoms (Abnormal discharge from the eyes)
Objective symptoms
   Edema of the eyelid, Conjunctival pigmentation, Cysts of meibomian glands,
   Cheesy secretion from meibomian glands,