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Table 5 Comparative basal gene expressions in various tissues. a

From: Feeding mice with diets containing mercury-contaminated fish flesh from French Guiana: a model for the mercurial intoxication of the Wayana Amerindians

   Tissues
Function Gene Hippocampus Liver Kidney Muscles
Mitochondrial metabolism CoxI 65.103 ± 11.103 2048 ± 1354 8192 ± 1214 104.104 ± 84.104
Oxidative stress Sod2 8 ± 6.8 256 ± 104 128 ± 8.5 2048 ± 279
  Sod3 4 ± 1.9 2 ± 1.4 16 ± 2.2 8 ± 4.3
Detoxication process Mt1 8 ± 2.5 4 ± 1.3 4 ± 0.9 4 ± 3.8
  Mt2 1024 ± 430 64 ± 3 64 ± 33 512 ± 482
  Gsta4 32 ± 27 512 ± 4.9 32 ± 4.4 256 ± 51
Apoptosis Bax 8 ± 3.2 16 ± 2.1 16 ± 8.8 512 ± 189
  Fos 4 ± 3.7 0.25 ± 0.01 0.5 ± 0.4 16 ± 9.5
  1. a Gene expressions in brain, liver, kidneys, and skeletal muscles from control mice after one month feeding with vegetal diet (mean ± SE, n = 3). B-actin was the reference gene.
  2. Bax: Bcl2-associated X protein; Cox I: cytochrome c oxidase subunit I; fos: FBJ osteosarcoma oncogene; Gsta4: glutathione S-transferase, alpha 4; Mt1: metallothionein isoform 1; Mt2: metallothionein isoform 2; Sod2: mitochondrial superoxide dismutase; Sod3: extracellular superoxide dismutase.