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Table 6 Absorbed permethrin dose estimated from creatinine-adjusted concentrations (C1) and amounts (A) of DCCA

From: Concentrations versus amounts of biomarkers in urine: a comparison of approaches to assess pyrethroid exposure

   Permethrin absorbed dose
  Relative creatinine excretion rate (A) Estimated from cumulative amounts (μg/kg bw/day) (C1) Estimated from creatinine-adjusted concentrationsa (μg/kg bw/day) C1/A
Adults     
   Urban     
  Lowestb 0.00625 0.0167 2.7
  5th percentilec 0.00749 0.0159 2.1
  Mediand 0.835 0.739 0.89
  95th percentilee 0.0153 0.0131 0.86
  Highestf 0.00912 0.00622 0.68
   Rural     
  Lowestb 0.0164 0.0340 2.1
  5th percentilec 0.0136 0.0167 1.2
  Mediand 0.0155 0.0191 1.2
  95th percentilee 0.0104 0.00722 0.69
  Highestf 0.0286 0.0142 0.50
Children     
   Urban     
  Lowestb 0.0185 0.0469 2.5
  5th percentilec 0.177 0.342 1.9
  Mediand 0.0120 0.00667 0.56
  95th percentilee 0.00754 0.00461 0.61
  Highestf 0.0818 0.0137 0.17
   Rural     
  Lowestb 0.00481 0.00932 1.9
  5th percentilec 0.00631 0.00670 1.1
  Mediand 0.0155 0.0189 1.2
  95th percentilee 0.0237 0.0153 0.65
  Highestf 0.0188 0.00786 0.42
  1. aCalculated according to the method of Fenske et al. [37]
  2. bAbsorbed dose estimates for the participant with the lowest creatinine excretion rate
  3. cAbsorbed dose estimates for the participant with the creatinine excretion rate closest to the 5th percentile value
  4. dAbsorbed dose estimates for the participants with the median creatinine excretion rate
  5. eAbsorbed dose estimates for the participant with the creatinine excretion rate closest to the 95th percentile value
  6. fAbsorbed dose estimates for the participant with the highest creatinine excretion rate