L-dopa and catecholamines in N2a-Rβ cells were measured by a fluorescent HPLC method. Amounts of L-dopa and dopamine were significantly higher in TCDD-exposed N2a-Rβ cells as compared to unexposed N2a-Rβ cells. Fold increase represents the ratios of the amounts in TCDD-exposed cells to those in unexposed cells. No change was observed in the amount of noradrenaline with or without TCDD exposure to N2a-Rβ cells.
Values are mean ± SD of four replicate determinations. ND, not detected. **P < 0.01.