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Table 3 Results of cancer incidence analyses in the Seveso population*, 1977-96.

From: Cancer incidence in the population exposed to dioxin after the "Seveso accident": twenty years of follow-up

Cancer sites (ICD-9 code) Zone A (high exposure) Zone B (medium exposure) Zone R (low exposure)
  N RR 95% CI N RR 95% CI N RR 95% CI
All cancers (140-208) 44 1.03 0.76-1.38 270 1.00 0.89-1.13 1808 0.96 0.91-1.00
   Digestive (150-159) 7 0.59 0.28-1.23 79 1.06 0.85-1.33 495 0.94 0.85-1.03
Esophagus (150) 0 - - 1 0.26 0.04-1.91 35 1.33 0.92-1.92
Stomach (151) 3 0.86 0.28-2.69 19 0.87 0.55-1.37 131 0.84 0.70-1.01
Colon (153) 2 0.68 0.17-2.72 19 1.04 0.66-1.64 137 1.04 0.87-1.26
Rectum (154) 0 - - 17 1.78 1.09-2.88 71 1.05 0.82-1.35
Liver (155) 0 - - 14 1.29 0.76-2.20 56 0.74 0.56-0.97
Biliary tract (156) 0 - - 6 2.28 1.00-5.17 16 0.82 0.49-1.39
Pancreas (157) 1 1.15 0.16-8.19 3 0.56 0.18-1.74 38 0.99 0.70-1.40
Other digestive (159) 1 6.96 0.96-50.6 0 - - 3 0.46 0.14-1.48
   Respiratory (160-165) 7 0.88 0.42-1.85 48 0.98 0.73-1.30 350 1.02 0.91-1.15
Lung (162) 7 1.12 0.53-2.36 37 0.96 0.69-1.33 280 1.04 0.92-1.19
Pleura (163) 0 - - 4 3.38 1.22-9.37 5 0.60 0.24-1.50
   Soft tissue sarcoma (171) 0 - - 0 - - 9 1.32 0.64-2.73
   Soft tissue and visceral sarcomas 0 - - 3 0.82 0.26-2.58 24 0.98 0.64-1.51
   Melanoma (172) 1 1.62 0.23-11.61 2 0.50 0.12-2.03 19 0.71 0.44-1.14
Skin (173) 3 1.39 0.45-4.32 5 0.37 0.15-0.90 88 0.93 0.75-1.17
   Breast (174) 8 1.43 0.71-2.87 30 0.85 0.59-1.22 249 1.00 0.88-1.15
   Genito-urinary tract (179-189) 8 1.07 0.53-2.14 46 0.98 0.73-1.31 302 0.91 0.81-1.03
   Uterus (179-182) 4 2.34 0.87-6.27 10 0.93 0.49-1.73 61 0.79 0.60-1.03
Cervix (180) 2 2.67 0.66-10.77 7 1.47 0.69-3.12 28 0.84 0.57-1.25
Endometrium (182) 1 1.24 0.17-8.82 3 0.60 0.19-1.87 27 0.73 0.49-1.10
   Ovary (183) 1 1.11 0.16-7.90 1 0.18 0.02-1.25 45 1.12 0.82-1.54
   Prostate (185) 0 - - 7 0.94 0.45-1.99 39 0.75 0.54-1.05
   Testis (186) 0 - - 2 0.82 0.20-3.32 22 1.44 0.90-2.31
   Bladder (188) 3 1.44 0.46-4.49 17 1.33 0.82-2.16 84 0.94 0.75-1.19
   Kidney (189) 0 - - 6 0.87 0.39-1.96 43 0.90 0.65-1.24
   Brain (191) 2 2.43 0.60-9.79 4 0.76 0.28-2.045 37 1.04 0.73-1.48
Thyroid (193) 1 2.63 0.37-18.86 4 1.60 0.59-4.36 19 1.15 0.70-1.89
Lymphatic and hematopoietic tissue
(200-208)
4 1.39 0.52-3.71 29 1.56 1.07-2.27 121 0.96 0.79-1.16
   All lymphoma (200-202) 1 0.62 0.09-4.41 15 1.43 0.86-2.40 72 1.02 0.80-1.32
   Hodgkin's disease (201) 0 - - 3 1.20 0.38-3.78 23 1.46 0.91-2.29
   Non-Hodgkin's lymphoma (200, 202) 1 0.80 0.11-5.69 12 1.51 0.85-2.69 49 0.90 0.66-1.22
   Multiple myeloma (203) 1 2.88 0.40-20.70 6 2.77 1.2-6.32 18 1.15 0.70-1.91
   Leukemia (204-208) 2 2.18 0.54-8.76 8 1.35 0.66-2.73 31 0.77 0.53-2.12
   Lymphatic leukemia (204) 1 2.78 0.39-19.9 0 - - 13 0.83 0.46-1.48
   Myeloid leukemia (205) 1 2.23 0.31-15.99 7 2.41 1.12-5.18 15 0.76 0.44-1.30
   Leukemia, unspecified (208) 0 - - 1 2.16 0.29-16.10 2 0.61 0.14-2.60
  1. *Subjects aged < 75 years, resident in the area at the accident time.
  2. ICD-9: International Classification of Diseases, Ninth Revision; N: number of cases; RR: rate ratios calculated with Poisson regression, adjusted for gender, age category, and period; 95% CI: 95% confidence interval.