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Table 3 Frequencies, Crude, Unadjusted and Adjusted GEE Odds Ratios (OR) and 95% Confidence Intervals (CI) for All Congenital Anomalies Combined by Prenatal PCE Exposure

From: Prenatal exposure to tetrachloroethylene-contaminated drinking water and the risk of congenital anomalies: a retrospective cohort study

  Number with Anomalies Total
Number
Crude OR
(95% CI)
Unadjusted
GEE OR
(95% CI)
Multivariate* GEE OR
(95% CI)
Any Exposure      
>0 61 1658 1.2 (0.8,1.6) 1.1 (0.8,1.6) 1.2 (0.8,1.7)
0 (referent) 95 2999 1.0 (--------) 1.0 (--------) 1.0 (--------)
Exposure Categorized by 1980 Action Level of 40 ug/L      
>1.136 g (40 ug/L) 26 605 1.4 (0.9,2.1) 1.4 (0.9,2.2) 1.4 (0.9,2.2)
>0 - <= 1.136 g 35 1053 1.1 (0.7,1.6) 1.0 (0.6,1.5) 1.0 (0.7,1.6)
0 (Referent) 95 2999 1.0 (--------) 1.0 (--------) 1.0 (---------)
Exposure Categorized in Quartiles      
>75th p'tile 19 415 1.5 (0.9, 2.4) 1.5 (0.9, 2.4) 1.5 (0.9, 2.5)
50th - <75th p'ctile 14 414 1.1 (0.6, 1.9) 1.0 (0.6, 1.9) 1.1 (0.6, 2.0)
25th - <50th p'ctile 15 415 1.1 (0.7, 2.0) 1.1 (0.6, 2.0) 1.1 (0.6, 2.0)
>0 - <25th p'ctile 13 414 1.0 (0.5, 1.8) 0.9 (0.5, 1.8) 1.0 (0.5, 1.9)
0 (referent) 95 2999 1.0 (---------) 1.0 (---------) 1.0 (---------)
  1. *Adjusted for maternal and paternal age