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Table 3 Frequencies, Crude, Unadjusted and Adjusted GEE Odds Ratios (OR) and 95% Confidence Intervals (CI) for All Congenital Anomalies Combined by Prenatal PCE Exposure

From: Prenatal exposure to tetrachloroethylene-contaminated drinking water and the risk of congenital anomalies: a retrospective cohort study

 

Number with Anomalies

Total

Number

Crude OR

(95% CI)

Unadjusted

GEE OR

(95% CI)

Multivariate* GEE OR

(95% CI)

Any Exposure

     

>0

61

1658

1.2 (0.8,1.6)

1.1 (0.8,1.6)

1.2 (0.8,1.7)

0 (referent)

95

2999

1.0 (--------)

1.0 (--------)

1.0 (--------)

Exposure Categorized by 1980 Action Level of 40 ug/L

     

>1.136 g (40 ug/L)

26

605

1.4 (0.9,2.1)

1.4 (0.9,2.2)

1.4 (0.9,2.2)

>0 - <= 1.136 g

35

1053

1.1 (0.7,1.6)

1.0 (0.6,1.5)

1.0 (0.7,1.6)

0 (Referent)

95

2999

1.0 (--------)

1.0 (--------)

1.0 (---------)

Exposure Categorized in Quartiles

     

>75th p'tile

19

415

1.5 (0.9, 2.4)

1.5 (0.9, 2.4)

1.5 (0.9, 2.5)

50th - <75th p'ctile

14

414

1.1 (0.6, 1.9)

1.0 (0.6, 1.9)

1.1 (0.6, 2.0)

25th - <50th p'ctile

15

415

1.1 (0.7, 2.0)

1.1 (0.6, 2.0)

1.1 (0.6, 2.0)

>0 - <25th p'ctile

13

414

1.0 (0.5, 1.8)

0.9 (0.5, 1.8)

1.0 (0.5, 1.9)

0 (referent)

95

2999

1.0 (---------)

1.0 (---------)

1.0 (---------)

  1. *Adjusted for maternal and paternal age