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Table 2 Latencies, LRT, fitted parameters, ERR and bootstrap confidence intervals for the two-phase model

From: Reanalysis of cancer mortality in Japanese A-bomb survivors exposed to low doses of radiation: bootstrap and simulation methods

Site ϕmabs ϕm ERR1 ERR0.025
Stom 11.89 11.89 21.19 19.64 0.46 120.01 82.67 0.46 (0.21, 0.80)bca (0.19, 0.79)per 0.39 (0.15, 0.70)bca (0.15, 0.71)per
Liver 36.90 36.90 34.87 27.64 1.43 291.22 76.76 1.43 (0.70, 2.41)bca (0.72, 2.39)per 1.10 (0.49, 1.90)bca (0.40, 1.88)per
Lung 36.99 13.60 16.04 14.74 0.44 37.90 4.46 0.88 (0.34, 1.50)bca (0.27, 2.07)per 0.86 (0.40, 1.49)bca (0.32, 2.02)per
Panc 11.86 11.86 16.22 14.80 9.77 1060.94 43.77 9.77 (3.50a, 14.27)bca (1.72, 55.11)per 9.12 (3.25b, 13.46)bca (1.49, 48.25)per
Leuk 23.66 23.66 25.40 25.29 1.69 3353.15 172.25 1.69 (0.20, 4.81)bca (0.19, 4.77)per 1.17 (0.18, 3.58)bca (0.24, 3.79)per
  1. ϕmabs: latency (years) which maximises LRT 2p-con
  2. ϕm: optimal latency, which maximises LRT 2p-con with the constraint ERR1 ≥ 0
  3. : Likelihood Ratio Test for the two-phase model against the control model at ϕm
  4. : Likelihood Ratio Test for the two-phase model against the linear model at ϕm
  5. : fitted parameters for the two-phase model at ϕm
  6. ERR1 : Excess Relative Risk at 10 mSv (lagged by ϕm), as estimated from the fitted two-phase model
  7. ERR0.025 : Excess Relative Risk at 0.25 mSv (lagged by ϕm), as estimated from the fitted two-phase model
  8. bca Bootstrap BCa 95%CI (5000 bootstrap replications)
  9. per Bootstrap percentile 95%CI (1000 bootstrap replications)
  10. a : minimum bootstrap value, lower tail probability = 0.034
  11. b : minimum bootstrap value, lower tail probability = 0.024