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Table 2 Latencies, LRT, fitted parameters, ERR and bootstrap confidence intervals for the two-phase model

From: Reanalysis of cancer mortality in Japanese A-bomb survivors exposed to low doses of radiation: bootstrap and simulation methods

Site

Ï•mabs

Ï•m

ERR1

ERR0.025

Stom

11.89

11.89

21.19

19.64

0.46

120.01

82.67

0.46

(0.21, 0.80)bca

(0.19, 0.79)per

0.39

(0.15, 0.70)bca

(0.15, 0.71)per

Liver

36.90

36.90

34.87

27.64

1.43

291.22

76.76

1.43

(0.70, 2.41)bca

(0.72, 2.39)per

1.10

(0.49, 1.90)bca

(0.40, 1.88)per

Lung

36.99

13.60

16.04

14.74

0.44

37.90

4.46

0.88

(0.34, 1.50)bca

(0.27, 2.07)per

0.86

(0.40, 1.49)bca

(0.32, 2.02)per

Panc

11.86

11.86

16.22

14.80

9.77

1060.94

43.77

9.77

(3.50a, 14.27)bca

(1.72, 55.11)per

9.12

(3.25b, 13.46)bca

(1.49, 48.25)per

Leuk

23.66

23.66

25.40

25.29

1.69

3353.15

172.25

1.69

(0.20, 4.81)bca

(0.19, 4.77)per

1.17

(0.18, 3.58)bca

(0.24, 3.79)per

  1. Ï•mabs: latency (years) which maximises LRT 2p-con
  2. ϕm: optimal latency, which maximises LRT 2p-con with the constraint ERR1 ≥ 0
  3. : Likelihood Ratio Test for the two-phase model against the control model at Ï•m
  4. : Likelihood Ratio Test for the two-phase model against the linear model at Ï•m
  5. : fitted parameters for the two-phase model at Ï•m
  6. ERR1 : Excess Relative Risk at 10 mSv (lagged by Ï•m), as estimated from the fitted two-phase model
  7. ERR0.025 : Excess Relative Risk at 0.25 mSv (lagged by Ï•m), as estimated from the fitted two-phase model
  8. bca Bootstrap BCa 95%CI (5000 bootstrap replications)
  9. per Bootstrap percentile 95%CI (1000 bootstrap replications)
  10. a : minimum bootstrap value, lower tail probability = 0.034
  11. b : minimum bootstrap value, lower tail probability = 0.024