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Table 8 simulated null distribution of LRT2p-con and LRT2p-lin including "city", by dose range

From: Reanalysis of cancer mortality in Japanese A-bomb survivors exposed to low doses of radiation: bootstrap and simulation methods

Dose range

Site

Φm

LRT2p-con

Shape

LRT2p-con

Rate

t 0.95

LRT2p-lin

shape

LRT2p-lin

rate

T 0.95

0-20

Stom

11

2.38

0.59

9.06

1.98

0.65

7.25

5-500

Stom

8

2.03

0.62

7.72

1.30

0.55

6.42

0-20

Liver

37

2.50

0.73

7.63

1.69

0.64

6.58

5-500

Liver

37

1.62

0.49

8.39

1.14

0.53

6.16

0-20

Lung

16

2.47

0.58

9.43

2.09

0.68

7.20

5-500

Lung

16

1.81

0.61

7.26

1.38

0.66

5.58

0-20

Panc

10

2.35

0.61

8.65

2.13

0.71

6.93

5-500

Panc

42

1.72

0.52

8.18

1.18

0.60

5.61

0-20

Leuk

25

2.11

0.62

7.94

1.59

0.67

6.01

5-500

Leuk

28

1.87

0.62

7.34

1.25

0.56

6.14

  1. gamma distributions are fitted to 500 simulations of LRT2p-con for the null hypothesis (β0,σ0,τ0) = (0,0, arbitrary) and of LRT2p-lin for the null hypothesis (β0,σ0,τ0) = (,0, arbitrary) where is the fitted parameter for the linear model. Models include "city" as a control covariate and are fitted at the optimal (integral) latency Φm for the site and dose range.
  2. shape: shape parameter of the fitted gamma distribution
  3. rate: rate parameter of the fitted gamma distribution
  4. t 0.95 : critical value of the fitted gamma distribution for
  5. T 0.95 : critical value of the fitted gamma distribution for