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Table 4 Linear regression analysis of log(nonHDL) on 2,4-D and covariates for ages 20-59, NHANES III, 1988-1994.

From: Perturbation of lipids and glucose metabolism associated with previous 2,4-D exposure: a cross-sectional study of NHANES III data, 1988-1994

Independent variables

All available subjects (n = 709)

Susceptible subpopulations

  

HbA1c > 5.1%

T4 ≤ 8.5 μg/dl

  

(n = 345)

(n = 345)

 

Estimate (95% CI)

Estimate (95% CI)

Estimate (95% CI)

Intercept

5.299

5.239

5.690

 

(4.907, 5.691)a

(4.660, 5.818)a

(5.141, 6.239)a

2,4-D, binary

-0.205

-0.187

-0.270

 

(-0.989, 0.579)

(-1.379, 1.005)

(-1.303, 0.764)

Log(HDL) for 2,4-D < LOD

-0.191

-0.179

-0.254

 

(-0.274, -0.109)a

(-0.305, -0.054)b

(-0.369, -0.139)a

Log(HDL) fo4 2,4-D ≥ LOD

-0.140

-0.124

0.187

 

(-0.336, 0.056)

(-0.417, 0.168)

(-0.442, 0.067)

Log (urinary creatinine)

0.001

0.009

-0.035

 

(-0.030, 0.031)

(-0.036, 0.054)

(-0.078, 0.008)

Gender

0.046

0.058

0.086

 

(0.002, 0.089)c

(-0.006, 0.121)

(0.023, 0.149)b

Age (years)

0.007

0.008

0.007

 

(0.005, 0.009)a

(0.005, 0.010)a

(0.004, 0.010)a

Non-Hispanic Black

-0.058

-0.073

-0.042

 

(-0.107, -0.008)c

(-0.148, 0.002)

(-0.111, 0.027)

Mexican American

0.032

0.028

0.041

 

(-0.021, 0.084)

(-0.053, 0.108)

(-0.038, 0.120)

Other ethnicity

-0.002

-0.067

0.014

 

(-0.124, 0.121)

(-0.234, 0.100)

(-0.154, 0.181)

Past smoker

0.043

0.041

0.026

 

(-0.012, 0.098)

(-0.037, 0.120)

(-0.049, 0.101)

Active smoker

0.043

0.022

0.023

 

(-0.003, 0.088)

(-0.045, 0.088)

(-0.041, 0.088)

BMI 25-29 kg/m2

0.128

0.084

0.148

 

(0.081, 0.174)a

(0.013, 0.155)c

(0.084, 0.213)a

BMI ≥ 30 kg/m2

0.218

0.153

0.212

 

(0.163, 0.273)a

(0.77, 0.229)a

(0.132, 0.292)a

Alcohol consumption

0.014

0.019

-0.020

 

(-0.058, 0.085)

(-0.81), 0.120)

(-0.107, 0.068)

Income ≥ 20K (%)

0.053

0.057

0.047

 

(0.011, 0.095)c

(-0.003, 0.117)

(-0.014, 0.107)

Hours of fasting

-0.003

-0.002

-0.004

 

(-0.007, 0.002)

(-0.008, 0.005)

(-0.011, 0.002)

  1. a p ≤ 0.001, b p ≤ 0.01, c p ≤ 0.05
  2. P-values for the interaction term log(HDL)*2,4-D are 0.62 for all subjects, 0.73 for subjects with HbA1c > 5.1%, and 0.63 for subjects with T4 ≤ 8.5 μg/dl.