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Table 4 Linear regression analysis of log(nonHDL) on 2,4-D and covariates for ages 20-59, NHANES III, 1988-1994.

From: Perturbation of lipids and glucose metabolism associated with previous 2,4-D exposure: a cross-sectional study of NHANES III data, 1988-1994

Independent variables All available subjects (n = 709) Susceptible subpopulations
   HbA1c > 5.1% T4 ≤ 8.5 μg/dl
   (n = 345) (n = 345)
  Estimate (95% CI) Estimate (95% CI) Estimate (95% CI)
Intercept 5.299 5.239 5.690
  (4.907, 5.691)a (4.660, 5.818)a (5.141, 6.239)a
2,4-D, binary -0.205 -0.187 -0.270
  (-0.989, 0.579) (-1.379, 1.005) (-1.303, 0.764)
Log(HDL) for 2,4-D < LOD -0.191 -0.179 -0.254
  (-0.274, -0.109)a (-0.305, -0.054)b (-0.369, -0.139)a
Log(HDL) fo4 2,4-D ≥ LOD -0.140 -0.124 0.187
  (-0.336, 0.056) (-0.417, 0.168) (-0.442, 0.067)
Log (urinary creatinine) 0.001 0.009 -0.035
  (-0.030, 0.031) (-0.036, 0.054) (-0.078, 0.008)
Gender 0.046 0.058 0.086
  (0.002, 0.089)c (-0.006, 0.121) (0.023, 0.149)b
Age (years) 0.007 0.008 0.007
  (0.005, 0.009)a (0.005, 0.010)a (0.004, 0.010)a
Non-Hispanic Black -0.058 -0.073 -0.042
  (-0.107, -0.008)c (-0.148, 0.002) (-0.111, 0.027)
Mexican American 0.032 0.028 0.041
  (-0.021, 0.084) (-0.053, 0.108) (-0.038, 0.120)
Other ethnicity -0.002 -0.067 0.014
  (-0.124, 0.121) (-0.234, 0.100) (-0.154, 0.181)
Past smoker 0.043 0.041 0.026
  (-0.012, 0.098) (-0.037, 0.120) (-0.049, 0.101)
Active smoker 0.043 0.022 0.023
  (-0.003, 0.088) (-0.045, 0.088) (-0.041, 0.088)
BMI 25-29 kg/m2 0.128 0.084 0.148
  (0.081, 0.174)a (0.013, 0.155)c (0.084, 0.213)a
BMI ≥ 30 kg/m2 0.218 0.153 0.212
  (0.163, 0.273)a (0.77, 0.229)a (0.132, 0.292)a
Alcohol consumption 0.014 0.019 -0.020
  (-0.058, 0.085) (-0.81), 0.120) (-0.107, 0.068)
Income ≥ 20K (%) 0.053 0.057 0.047
  (0.011, 0.095)c (-0.003, 0.117) (-0.014, 0.107)
Hours of fasting -0.003 -0.002 -0.004
  (-0.007, 0.002) (-0.008, 0.005) (-0.011, 0.002)
  1. a p ≤ 0.001, b p ≤ 0.01, c p ≤ 0.05
  2. P-values for the interaction term log(HDL)*2,4-D are 0.62 for all subjects, 0.73 for subjects with HbA1c > 5.1%, and 0.63 for subjects with T4 ≤ 8.5 μg/dl.