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Table 2 Distribution between exposure groups and risk of ever experiencing a pregnancy loss in categories of CB-153 exposure in relation to the lowest CB-153 exposure group

From: Fetal loss and maternal serum levels of 2,2',4,4',5,5'-hexachlorbiphenyl (CB-153) and 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (p,p'-DDE) exposure: a cohort study in Greenland and two European populations

 

CB-153 (ng/g lipid)

 

0-25

25-50

50-100

100-200

>200

Continuous

(Per 1 log unit)

Greenland

      

Number of women with at least one previous pregnancy

33

52

113

115

116

429

Number of women ever who ever experienced a fetal loss

12

24

48

49

68

201

Number of women with only one previous pregnancy

13

28

41

37

30

149

Number of women experiencing fetal loss in one pregnancy

2

8

9

5

9

33

   Preg adj. odds ratio. (95%CI) a

1

1.7 (0.7-4.5)

1.1 (0.5-2.6)

1.0 (0.4-2.4)

1.6 (0.7-3.7)

1.1 (0.9-1.3)

   Adj. odds ratio (95%CI) b

1

1.6 (0.4-6.2)

1.3 (0.4-4.3)

0.8 (0.2-2.8)

1.6 (0.5-5.5)

1.0 (0.7-1.3)

   Adj. OR one prev. pregnancy

1

1.2 (0.2-8.5)

0.8 (0.1-4.9)

0.8 (0.1-5.6)

1.7 (0.3-11.7)

1.2 (0.7-2.0)

Kharkiv

      

Number of women with at least one previous pregnancy

81

85

33

1

0

200

Number of women ever who ever experienced a fetal loss

16

23

10

1

0

50

Number of women with only one previous pregnancy

46

50

21

1

0

118

Number of women experiencing fetal loss in one pregnancy

7

9

4

1

0

21

   Preg adj. odds ratio. (95%CI) a

1

1.5 (0.7-3.2)

1.8 (0.6-4.7)

-

-

1.6 (0.9-2.8)

   Adj odds ratio (95%CI) b

1

1.6 (0.7-3.7)

1.7 (0.6-5.2)

-

-

1.4 (0.7-2.8)

   Adj. OR one prev. pregnancy

1

1.2 (0.4-4.1)

1.3 (0.3-6.2)

-

-

1.0 (0.4-2.4)

Warsaw n

      

Number of women with at least one previous pregnancy

45

4

0

0

0

49

Number of women ever who ever experienced a fetal loss

30

4

0

0

0

34

Number of women with only one previous pregnancy

39

2

0

0

0

41

Number of women experiencing fetal loss in one pregnancy

25

2

0

0

0

27

   Preg adj. odds ratio. (95%CI) a

1

-

-

-

-

2.5 (1.0-5.9)

   Adj odds ratio (95%CI) b

1

-

-

-

-

1.4 (0.1-78.8)

   Adj. OR one prev. pregnancy

1

-

-

-

-

4.7 (1.2-18.3)

Combined c

      

Number of women with at least one previous pregnancy

159

141

146

116

116

678

Number of women ever who ever experienced a fetal loss

58

51

58

50

68

285

Number of women with only one previous pregnancy

98

80

62

38

30

308

Number of women experiencing fetal loss in one pregnancy

34

19

13

6

9

81

   Preg adj. odds ratio (95%CI) a

1

1.7 (1.0-3.0)

1.4 (0.8-2.6)

1.3 (0.7-2.5)

1.9 (1.0-3.8)

1.2 (1.0-1.4)

   Adj odds ratio (95%CI) b

1

1.9 (0.9-3.9)

1.9 (0.9-4.0)

1.4 (0.6-3.2)

2.4 (1.1-5.5)

1.2 (1.0-1.5)

   Adj. OR one prev. pregnancy

1

1.6 (0.6-4.2)

1.6 (0.5-4.7)

1.3 (0.3-5.1)

2.5 (0.7-9.2)

1.4 (0.9-2.0)

  1. a Adjusted for number of previous pregnancies. b Adjusted for age, number of previous pregnancies, smoking, alcohol consumption, urogenital diseases, urogenital infections, chronic diseases, body mass index and two or more previous induced abortions. c Calculated odds ratios are all adjusted for country.
  2. "-" refers to missing results due too low number of individuals in the strata to perform the desired analyses