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Table 5 Final Hierarchical Multivariate Models of Lung Function and Asthma Severity.

From: An integrated model of environmental factors in adult asthma lung function and disease severity: a cross-sectional study

Models and covariates

Percent predicted

FEV1

 

Severity of Asthma

Score

 

β

se

p

 

β

se

p

Sociodemographics and behavioral characteristics

      

   Age (years)

-0.56

0.15

<0.001

 

0.10

0.05

0.03

   High school education or less

-9.25

3.67

0.01

    

   Not employed

-4.48

3.14

0.16

 

1.75

1.05

0.10

   Currently employed, VGDF (ref: employed, no VGDF)

-0.74

2.83

0.80

 

1.75

0.91

0.06

   Light smoker (<10 pack years)

1.01

3.03

0.74

    

   Heavy smoker (≥10 pack years) (ref: never smoked)

3.76

4.40

0.39

    

Adj. R2 (cumulative)

0.12 *

 

0.07 *

Household biologics and antigen-antibody status

      

   Total dust wt bedroom (per 100 g)

-2.23

0.58

<0.001

    

   Dog owner

    

0.80

0.85

0.34

   Elevated anti-Can f1 specific IgE

-9.79

3.28

0.003

 

2.81

1.08

0.01

Adj. R2 (cumulative)

0.22 *

 

0.10 *

Indoor air quality

       

   Wall dampness, % moisture

    

-0.23

0.16

0.17

   Any houseplants

    

-1.52

1.10

0.17

   Air filter in home

-2.89

2.76

0.30

 

1.95

0.89

0.03

   Coal/wood heat (vs. electric or gas)

1.31

3.82

0.73

 

-1.82

1.23

0.14

Adj. R2 (cumulative)

0.21

 

0.14 *

Metals in BR dust (upper quartile)

       

   Copper

    

-1.84

1.04

0.08

   Iron

    

-1.67

0.95

0.08

   Magnesium

4.40

2.85

0.13

    

   Zinc

    

1.26

1.05

0.23

Adj. R2 (cumulative)

0.21

 

0.17 *

External environment

       

   Census Block Group Factors

       

Factor 1: Poor (working/unemployed)

    

0.36

0.39

0.35

Factor 2: Suburban homeowners

-4.38

1.53

0.005

    

   Distance (m) to nearest road

0.28

0.08

<0.001

 

-0.02

0.03

0.41

   Urban/built environment

5.23

3.30

0.11

 

-1.44

1.03

0.16

   Air Quality Factor 2: Higher NO2, summer wind speed, and winter temperature; lower winter wind speed

-2.11

0.93

0.03

 

0.28

0.30

0.36

Adj. R2 (full model)

0.30 *

 

0.16

  1. * Added variables contribute significantly to explanatory power of model (p < 0.05) Parameter estimates and significance tests are from full model.
  2. Cumulative R2 calculated from models containing all preceding variables Higher Severity of Asthma scores indicate greater severity.