From: Cardiovascular effects of sub-daily levels of ambient fine particles: a systematic review
Authors | Subjects | Design | Exposure Levels | Dur. | Lags | PL | F | t-PA Agc |
---|---|---|---|---|---|---|---|---|
Rückerl et al., 2007 | Aged 51-76 yrs, with CVD | Epi. | Fixed site PM2.5 daily mean: 20 μg/m3 (SD15); UFP nb, PM10 also measured; | 6 hb | Lag0, 6, 12, 18 h | ↓ with UFP lag 0 and 18 h |  |  |
Carlsten et al., 2007 | Mean age 25 yrs (21-43) | Exp. | Diesel PM: 100 and 200 μg/m3 | 2 h | Lag3, 6, 22 h | - |  |  |
Frampton et al., 2004 | Aged 18-40 yrs, 57% asthmatics | Exp. | UFP: 10 or 25 μg/m3; with exercise; | 2 h | Lag0, 3.5, 15, 21, 45 h | - | - |  |
Ghio et al., 2000 | Mean age 26 yrs (SD1) | Exp. | CAP~PM2.5: 23-311 μg/m3; with exercise; | 2 h | Lag18 h | - | ↑ |  |
Gong et al., 2008 | Aged 18-50 yrs, 45% asthmatics | Exp. | CAP~UFP: 100 μg/m3 (SD68); with exercise; | 2 h | Lag0, 4, 22 h | - | - | - |
Gong et al., 2004b | Aged 54-85 yrs, 68% COPD | Exp. | CAP~PM2.5 : 167 (SD27) μg/m3; with exercise; | 2 h | Lag0, 4, 22 h | - | - |  |
Gong et al., 2003 | Aged 18-45 yrs, 50% asthmatics | Exp. | CAP~PM2.5 : 174 μg/m3 (SD37); with exercise; | 2 h | Lag0, 4, 22 h | - | - |  |
Lucking et al., 2008 | Aged 21-44 yrs | Exp. | Diesel PM: 350 μg/m3; | 2 h | Lag2 and 6 h | - |  |  |
Mills et al., 2008 | Mean age 54 yrs (SD2), 50% CVD | Exp. | CAP~PM2.5 : 190 μg/m3 (SD37); with exercise; | 2 h | Lag2, 6, 8 h | ↑ at lag2 |  | - |
Mills et al., 2007b | Mean age 60 yrs (SD1), with prior MI | Exp. | Diesel PM: 300 μg/m3; with exercise; | 1 h | Lag6, 24 h |  |  | ↓ at lag6 |
Mills et al., 2005 | Aged 20-38 yrs | Exp. | Diesel PM: 300 μg/m3; with exercise; | 1 h | Lag2, 6, 24 h | - |  | ↓ at lag6 |
Routledge et al., 2006 | Aged 52-75 yrs, 50% CVD | Exp. | C UFP: 50 μg/m3; | 1 h | Lag4 and 24 h | - | - |  |
Salvi et al. 1999 | Aged 21-28 yrs | Exp. | Diesel PM: 300 μg/m3; with exercise; | 1 h | Lag 6 h | ↑ |  |  |
Scharrer et al., 2007 | Mean age 29 yrs (SD8) | Exp. | Welding fume PM 50th: 3500 μg/m3 (1000-25300); | 1 h | Lag 5 h |  | - |  |
Törnqvist et al., 2007 | Mean age 26 yrs (18-38) | Exp. | Diesel PM: 300 μg/m3; with exercise; | 1 h | Lag 24 h | - |  | - |