|
Unadjusted (N = 1675)
|
Adjusted1 (N = 1461)
|
Unadjusted (N = 1675)
|
Adjusted1 (N = 1460)
|
Unadjusted (N = 1671)
|
Adjusted1 (N = 1463)
|
---|
| |
Current wheezing
|
Ever having wheezed
|
Ever asthma
|
Cumulative PM at 50 m
|
> 50 m, None
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
|
< 50 m, Low
|
1.17 (0.80,1.73)
|
1.06 (0.66,1.70)
|
1.29 (0.89,1.88)
|
1.30 (0.83,2.04)
|
0.96 (0.56,1.66)
|
0.84 (0.45,1.57)
|
|
< 50 m, High2
|
1.97 (1.23,3.16)
|
2.33 (1.27,1.30)
|
1.32 (0.83,2.09)
|
1.66 (0.91,3.01)
|
1.78 (0.97,3.25)
|
2.51 (1.36,4.64)
|
Cumulative PM at 100 m
|
> 100 m, None
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
|
< 100, Low
|
1.00 (0.68,1.46)
|
1.08 (0.72,1.63)
|
1.16 (0.86,1.56)
|
1.24 (0.89,1.72)
|
0.97 (0.66,1.40)
|
0.85 (0.56,1.29)
|
|
< 100, High2
|
1.86 (1.17,2.97)
|
1.92 (1.06,3.46)
|
1.29 (0.85,1.95)
|
1.41 (0.94,2.38)
|
1.72 (1.02,2.90)
|
2.00 (1.11,3.51)
|
Cumulative PM at 150 m
|
> 150 m, None
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
|
< 150, Low
|
0.98 (0.64,1.50)
|
1.05 (0.66,1.67)
|
1.00 (0.72,1.38)
|
1.10 (0.74,1.62)
|
0.88 (0.58,1.33)
|
0.83 (0.52,1.32)
|
|
< 150, Medium
|
0.98 (0.61,1.57)
|
1.19 (0.71,1.97)
|
1.02 (0.67,1.57)
|
1.17 (0.74,1.82)
|
0.88 (0.52,1.47)
|
0.97 (0.57,1.62)
|
|
< 150, High2
|
1.58 (0.91,2.73)
|
1.60 (0.79,3.22)
|
1.58 (1.13,2.21)
|
1.51 (0.95,2.41)
|
1.29 (0.81,2.05)
|
1.31 (0.77,2.22)
|
|
P-value for trend
|
0.20
|
0.16
|
0.05
|
0.10
|
0.67
|
0.61
|
Cumulative NOx at 50 m
|
> 50 m, None
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
|
< 50 m, Low
|
1.12 (0.79,1.57)
|
1.08 (0.64,1.54)
|
1.17 (0.84,1.61)
|
1.24 (0.84,1.85)
|
1.02 (0.63,1.64)
|
0.96 (0.58,1.59)
|
|
< 50 m, High2
|
2.12 (1.26,3.58)
|
2.14 (1.05,4.35)
|
1.71 (1.07,2.73)
|
1.83 (0.94,3.57)
|
1.58 (0.86,2.87)
|
1.90 (0.94,3.82)
|
Cumulative NOx at 100 m
|
> 100 m, None
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
|
< 100, Low
|
1.01 (0.71,1.44)
|
1.11 (0.75,1.63)
|
1.10 (0.83,1.47)
|
1.19 (0.86,1.63)
|
0.96 (0.67,1.37)
|
0.85 (0.57,1.27)
|
|
< 100, High2
|
1.78 (1.06,2.96)
|
1.76 (0.93,3.30)
|
1.49 (0.98,2.26)
|
1.61 (0.95,2.71)
|
1.72 (0.96,3.09)
|
1.89 (1.00,3.57)
|
Cumulative NOx at 150 m
|
> 150 m, None
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
|
< 150, Low
|
1.01 (0.69,1.48)
|
1.14 (0.75,1.71)
|
1.01 (0.75,1.28)
|
1.14 (0.81,1.61)
|
0.89 (0.60,1.31)
|
0.89 (0.58,1.37)
|
|
< 150, Medium
|
0.90 (0.47,1.72)
|
1.12 (0.57,2.19)
|
0.99 (0.71,1.54)
|
1.09 (0.58,2.03)
|
0.76 (0.37,1.58)
|
0.84 (0.39,1.78)
|
|
< 150, High2
|
1.56 (0.97,2.52)
|
1.44 (0.75,2.74)
|
1.58 (0.96,1.69)
|
1.47 (1.01,2.15)
|
1.38 (0.83,2.27)
|
1.27 (0.72,2.26)
|
|
P-value for trend
|
0.20
|
0.25
|
0.04
|
0.12
|
0.59
|
0.71
|
-
1Adjusted for gender, smoking during pregnancy, co-morbidity and all other risk factors except birthweight, 2 Cut-off points for levels of exposure were defined based on the 50% (in the case of the medium category) and/or 75% (i.e. highest quartile for the high category) of the distribution of non-zero values.