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Table 4 The % change in the levels of hs CRP, soluble VCAM-1, and soluble ICAM-1 for a 5°C decrease in ambient temperature excluding the extreme temperatures

From: Associations between outdoor temperature and markers of inflammation: a cohort study

 

2.5% Hottest and coldest excluded

 

% Change

95% CI

C-reactive protein

  

Lag 0

7.16 *

0.33, 14.5

Lag 1

4.41

-2.61, 11.9

1 week

1.69

-8.29, 12.7

2 weeks

8.26

-4.84, 23.1

3 weeks

20.5 *

3.51, 40.2

4 weeks

29.2 *

2.93, 45.1

Soluble vascular cell adhesion molecule-1

 

Lag 0

-1.00

-3.16, 1.20

Lag 1

0.92

-1.41, 3.32

1 week

1.37

-1.14, 7.82

2 weeks

3.24

-2.45, 8.99

3 weeks

3.35

-1.77, 8.85

4 weeks

6.70 *

0.75, 13.0

Soluble intercellular adhesion molecule-1

 

Lag 0

0.55

-0.92, 2.03

Lag 1

0.41

-1.14, 1.98

1 week

0.77

-1.53, 3.12

2 weeks

1.72

-1.17, 4.70

3 weeks

3.84 *

0.45, 7.34

4 weeks

6.01 *

2.10, 10.1

  1. * P-value < 0.05
  2. a Model adjusted for relative humidity, barometric pressure, season, time trend, weekday, age, smoking, use of any anti-hypertensive medication and statins, body mass index, hypertension, education, diabetes, alcohol use (≥ 2 drinks/day), and race