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Table 3 Estimated coefficients with p-values of PCBs and their subsets in relation to BISD at age of16 months, 2002-2004.

From: Neurodevelopmental toxicity of prenatal polychlorinated biphenyls (PCBs) by chemical structure and activity: a birth cohort study

Log transformed Maternal sera (N = 760) Cord sera (N = 258)
Exposure Variables MDI PDI MDI PDI
  β SE β SE β SE β SE
4 major PCBs (∑non-dioxin-like PCBs) -0.39 0.62 -0.59 0.73 -1.02 0.94 -1.95* 1.13
∑ Dioxin-like mono-ortho PCBs -1.60*** 0.45 -1.26** 0.53 -1.40* 0.72 -1.99** 0.87
∑Anti-estrogenic PCBs -0.47 0.61 -0.58 0.72 -0.93 0.94 -1.85 1.13
PCB 118 -1.17*** 0.39 -1.04** 0.46 -1.44** 0.64 -2.04*** 0.77
PCB 138 -0.30 0.59 -0.53 0.70 -1.35 0.91 -2.27** 1.09
PCB 153 -0.33 0.62 -0.63 0.73 -1.22 0.94 -2.14* 1.14
PCB 156 -1.46*** 0.43 -1.02** 0.50 -0.50 0.71 -0.63 0.86
PCB 170 -0.54 0.60 -0.58 0.71 -0.62 0.77 -1.90* 0.94
PCB 180 -0.36 0.61 -0.47 0.72 -0.55 0.94 -1.26 1.13
  1. *P < 0.1; **P < 0.05; *** P < 0.01; Regression parameter coefficients represent score change in PDI and MDI for a one-unit change in loge [exposure concentration ng/mg lipid].
  2. ∑4 major PCBs (non-dioxin-like PCBs), sum of PCB #138, #153, #170 and #180; ∑ Dioxin-like mono-ortho PCBs, sum of PCB #118, and #156; ∑Anti-estrogenic PCBs, sum of PCB #138, #156, #170, and #180
  3. After adjusting for district, HOME, sex, Raven score from multiple linear regression models.