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Table 4 Final full multiple linear regression models of dioxin-like mono-ortho PCBs *.

From: Neurodevelopmental toxicity of prenatal polychlorinated biphenyls (PCBs) by chemical structure and activity: a birth cohort study

Maternal sera (n = 760)
  MDI PDI
Variables Beta SE p value Beta SE p value
Dioxin-like mono-ortho PCBs (natural log transformed: ng/mg lipids) -1.60 0.45 < 0.001 -1.26 0.53 0.02
District: Michalovce vs. Svidnik -4.12 1.01 < 0.0001 -17.22 1.19 <0.0001
HOME score 1.23 0.10 < 0.0001 0.80 0.12 < 0.0001
Raven score 0.24 0.04 < 0.0001 0.25 0.04 < 0.0001
SEX: male vs. female 3.27 0.78 < 0.0001 3.40 0.92 0.0002
Cord sera (n = 258)
  MDI PDI
Variables Beta SE p value Beta SE p value
Dioxin-like mono-ortho PCBs (natural log transformed: ng/mg lipids) -1.40 0.72 0.05 -1.99 0.87 0.02
District: Michalovce vs. Svidnik -4.15 1.77 0.02 -15.0 2.13 < 0.0001
HOME score 1.12 0.16 < 0.0001 0.64 0.19 <0.001
Raven score 0.20 0.06 0.001 0.38 0.08 < 0.0001
SEX: male vs. female 4.04 1.77 0.02 3.51 1.61 0.03
  1. * This final model provides an estimate of the effect of dioxin-like mono-ortho PCBs in maternal and cord sera on the Bayley scales (MDI and PDI), adjusting for district, HOME score, sex, maternal Raven's score.