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Table 3 Geometric mean infant meconium tobacco smoke metabolite concentration by prenatal tobacco smoke exposure.

From: A prospective cohort study of biomarkers of prenatal tobacco smoke exposure: the correlation between serum and meconium and their association with infant birth weight

  

Meconium NIC

Meconium COT

Meconium 3HC

 

N

% Detect

GM

(95% CI)

% Detect

GM

(95% CI)

% Detect

GM

(95% CI)

By Self-Reported Exposure

       

   Unexposed Both Periods

232

69.3

1.74 (1.50, 2.01)

60.3

0.10 (0.08, 0.12)

45.2

0.08 (0.06, 0.11)

   SHS Exposure 1 Period

21

85.7

2.20 (1.35, 3.59)

95.2

0.27 (0.12, 0.62)

85.7

0.32 (0.13, 0.81)

   SHS Exposure Both Periods

27

85.2

2.56 (1.67, 3.94)

77.8

0.20 (0.09, 0.40)

59.3

0.15 (0.07, 0.34)

   Active Exposure 1 Period

15

86.7

4.34 (2.44, 7.73)

93.3

0.92 (0.35, 2.43)

86.7

0.91 (0.31, 2.68)

   Active Exposure Both Periods

21

100

26.8 (16.6, 43.1)

100

15.9 (7.0, 36.2)

95.5

23.3 (9.5, 56.8)

By Mean Serum Cotinine

       

   Unexposed (< LOD)

131

70.6

1.50 (1.24, 1.82)

48.1

0.07 (0.05, 0.09)

33.8

0.05 (0.04, 0.07)

   SHS Exposure (LOD - 3 ng/mL)

170

83.9

2.08 (1.76, 2.45)

79.4

0.16 (0.12, 0.21)

65.3

0.15 (0.12, 0.21)

   Active Exposure (> 3 ng/mL)

37

94.7

21.3 (15.0, 30.1)

100

16.8 (9.7, 29.0)

97.4

21.3 (11.5, 39.3)

By Cumulative Serum Cotinine

       

   Unexposed all 3 Measures

61

71.2

1.32 (0.99, 1.76)

50

0.05 (0.03, 0.07)

30.0

0.03 (0.02, 0.05)

   SHS Exposure in 1 Measure

61

65.5

1.57 (1.18, 2.10)

46.7

0.08 (0.05, 0.12)

40.0

0.07 (0.04, 0.11)

   SHS Exposure in 2 Measures

41

71.8

1.70 (1.20, 2.42)

65

0.09 (0.05, 0.14)

40.0

0.07 (0.04, 0.12)

   SHS Exposure in 3 Measures

92

89.2

2.41 (1.92, 3.03)

89.4

0.19 (0.14, 0.26)

72.5

0.18 (0.12, 0.27)

   Active Exposure in 1 Measure

14

92.9

4.87 (2.71, 8.75)

100

2.77 (1.20, 6.37)

92.9

1.98 (0.75, 5.25)

   Active Exposure in 2 Measures

3

100

24.6 (6.92, 87.3)

100

13.3 (2.20, 80.5)

100

20.6 (2.50, 170)

   Active Exposure in 3 Measures

22

95.6

27.6 (17.5, 43.7)

100

20.6 (10.6, 40.0)

100

32.3 (15.1, 69.3)

  1. Concentration in ng/g