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Table 3 Geometric mean infant meconium tobacco smoke metabolite concentration by prenatal tobacco smoke exposure.

From: A prospective cohort study of biomarkers of prenatal tobacco smoke exposure: the correlation between serum and meconium and their association with infant birth weight

   Meconium NIC Meconium COT Meconium 3HC
  N % Detect GM
(95% CI)
% Detect GM
(95% CI)
% Detect GM
(95% CI)
By Self-Reported Exposure        
   Unexposed Both Periods 232 69.3 1.74 (1.50, 2.01) 60.3 0.10 (0.08, 0.12) 45.2 0.08 (0.06, 0.11)
   SHS Exposure 1 Period 21 85.7 2.20 (1.35, 3.59) 95.2 0.27 (0.12, 0.62) 85.7 0.32 (0.13, 0.81)
   SHS Exposure Both Periods 27 85.2 2.56 (1.67, 3.94) 77.8 0.20 (0.09, 0.40) 59.3 0.15 (0.07, 0.34)
   Active Exposure 1 Period 15 86.7 4.34 (2.44, 7.73) 93.3 0.92 (0.35, 2.43) 86.7 0.91 (0.31, 2.68)
   Active Exposure Both Periods 21 100 26.8 (16.6, 43.1) 100 15.9 (7.0, 36.2) 95.5 23.3 (9.5, 56.8)
By Mean Serum Cotinine        
   Unexposed (< LOD) 131 70.6 1.50 (1.24, 1.82) 48.1 0.07 (0.05, 0.09) 33.8 0.05 (0.04, 0.07)
   SHS Exposure (LOD - 3 ng/mL) 170 83.9 2.08 (1.76, 2.45) 79.4 0.16 (0.12, 0.21) 65.3 0.15 (0.12, 0.21)
   Active Exposure (> 3 ng/mL) 37 94.7 21.3 (15.0, 30.1) 100 16.8 (9.7, 29.0) 97.4 21.3 (11.5, 39.3)
By Cumulative Serum Cotinine        
   Unexposed all 3 Measures 61 71.2 1.32 (0.99, 1.76) 50 0.05 (0.03, 0.07) 30.0 0.03 (0.02, 0.05)
   SHS Exposure in 1 Measure 61 65.5 1.57 (1.18, 2.10) 46.7 0.08 (0.05, 0.12) 40.0 0.07 (0.04, 0.11)
   SHS Exposure in 2 Measures 41 71.8 1.70 (1.20, 2.42) 65 0.09 (0.05, 0.14) 40.0 0.07 (0.04, 0.12)
   SHS Exposure in 3 Measures 92 89.2 2.41 (1.92, 3.03) 89.4 0.19 (0.14, 0.26) 72.5 0.18 (0.12, 0.27)
   Active Exposure in 1 Measure 14 92.9 4.87 (2.71, 8.75) 100 2.77 (1.20, 6.37) 92.9 1.98 (0.75, 5.25)
   Active Exposure in 2 Measures 3 100 24.6 (6.92, 87.3) 100 13.3 (2.20, 80.5) 100 20.6 (2.50, 170)
   Active Exposure in 3 Measures 22 95.6 27.6 (17.5, 43.7) 100 20.6 (10.6, 40.0) 100 32.3 (15.1, 69.3)
  1. Concentration in ng/g