Association of maternal serum concentrations of 2,2', 4,4'5,5'-hexachlorobiphenyl (CB-153) and 1,1-dichloro-2,2-bis (p-chlorophenyl)-ethylene (p,p'-DDE) levels with birth weight, gestational age and preterm births in Inuit and European populations

Table 3 Regression coefficients¹ and odds ratios² (OR) from unadjusted and multivariate linear and logistic regression models of maternal serum log CB-153 and birth weight, gestational age and premature birth

	Birth weight (grams)			Gestational age (weeks)			Prematurity
	Regression coefficient	95% C.I.	p	Regression coefficient	95% C.I.	p	OR	95% C.I.	p
Unadjusted ³ model
Greenland	-87.6	(-132.9; -42.3)	< 0.01	-0.2	(-0.4; 0.0)	0.02	1.21	(0.93; 1.58)	0.16
Kharkiv	-24.6	(-75.2; 26.0)	0.34	-0.2	(-0.4; 0.0)	0.05	1.43	(0.78; 2.63)	0.26
Warsaw	-45.6	(-129.1; 37.9)	0.29	-0.1	(-0.5; 0.3)	0.62	0.93	(0.55; 1.58)	0.79
Multivariate model ^3,4
Greenland	-72.7	(-118.0; -27.4)	< 0.01	-0.2	(-0.4; 0.0)	0.02	1.14	(0.86; 1.52)	0.36
Kharkiv	-17.9	(-71.2; 35.4)	0.51	-0.1	(-0.3; 0.1)	0.12	1.28	(0.62; 2.65)	0.51
Warsaw	-61.6	(-152.3; 29.1)	0.19	-0.2	(-0.6; 0.2)	0.40	1.29	(0.65; 2.55)	0.47
Multivariate model, with gestational age
Greenland	-59.2	(-100.6; -17.8)	0.01
Kharkiv	-10.2	(-61.4; 41.0)	0.7
Warsaw	-49.4	(-134.5; 35.7)	0.26

¹Per one unit increase of natural log CB-153
²Per twofold increase of untransformed CB-153
³Number of subjects in unadjusted/multivariate models: Greenland birth weight 519/519, gestational age 547/547, prematurity 547/547; Kharkiv birth weight 565/554, gestational age 577/577, prematurity 577/577; Warsaw birth weight 186/186, gestational age 198/198, prematurity 198/198
⁴Models for birth weight controlled for: smoking status (Greenland); age of mother, mother's BMI, gender of child, number previous pregnancies, mother's martial status, passive smoking (Kharkiv); age of mother, gender of child, mother's education status, mother's BMI (Warsaw);
Models for gestational age controlled for: none (Greenland); mother's age (Kharkiv); mother's education level, mother's age, previous pregnancies, exposition, alcohol drinking (Warsaw);
Models for prematurity controlled for: mother's education level, mother's age, martial status (Greenland); mother's education level, previous pregnancies, smoking status, marital status, mother's age (Kharkiv); mother's BMI, mother's age (Warsaw);

ISSN: 1476-069X