Skip to main content
Figure 5 | Environmental Health

Figure 5

From: Combinations of physiologic estrogens with xenoestrogens alter calcium and kinase responses, prolactin release, and membrane estrogen receptor trafficking in rat pituitary cells

Figure 5

Xenoestrogens alter the amount of prolactin released by physiologic estrogens. The levels of prolactin (PRL) were measured in cells treated with (A-C) 10 pM of the physiologic estrogens (E2, E1, or E3 ) alone or in combinations with 10 pM of different alkylphenols (EP, PP, OP, NP, or BPA), row labeled lo PE - lo XE; (D-F) 1 nM of the physiologic estrogens alone or in combinations with 10 pM of different alkylphenols, row labeled hi PE - lo XE; (G-I) 10 pM of the physiologic estrogens alone or in combinations with 1 nM of different alkylphenols, row labeled lo PE - hi XE; (J-L) 1 nM of the physiologic estrogens alone or in combinations with 1 nM of different alkylphenols, row labeled hi PE - hi XE. * = p < 0.05 compared to vehicle (V) control cells. # = p < 0.05 compared to E2, E1, or E3 alone.

Back to article page