Movement of mERs in or out of the membrane in response to different physiologic (E
, or E
) or environmental (EP, PP, OP, NP, or BPA) estrogens. Levels were assessed by a quantitative plate assay measuring immunoreactive protein levels in the plasma membrane for ERα, ERβ, and GPER, after treatment with (A) 10 pM of estrogenic compounds or (B) 1 nM of estrogenic compounds for 5 min. *p < 0.05 compared to vehicle (V) control cells. #:p < 0.05 compared to E2, E1, or E3 alone.