Figure 6From: Combinations of physiologic estrogens with xenoestrogens alter calcium and kinase responses, prolactin release, and membrane estrogen receptor trafficking in rat pituitary cells Movement of mERs in or out of the membrane in response to different physiologic (E 2 , E 1 , or E 3 ) or environmental (EP, PP, OP, NP, or BPA) estrogens. Levels were assessed by a quantitative plate assay measuring immunoreactive protein levels in the plasma membrane for ERα, ERβ, and GPER, after treatment with (A) 10 pM of estrogenic compounds or (B) 1 nM of estrogenic compounds for 5 min. *p < 0.05 compared to vehicle (V) control cells. #:p < 0.05 compared to E2, E1, or E3 alone.Back to article page