|
Endpoint
|
Road test
|
Clean room
|
p-value for interaction
|
|---|
| |
Percent change (95%CI)
|
p-value
|
Percent change (95%CI)
|
p-value
|
Exposure scenario*
|
UFP†
|
PM2.5
‡
|
|---|
|
Exhaled NO,
|
-4.4% (-8.3% to -0.37%)
|
0.04
|
-1.3% (-6.5% to 4.1%)
|
0.63
|
0.38
|
0.63
|
0.50
|
|
PFA closure time
|
6.5% (-1.0% to 14.5%)
|
0.10
|
5.1% (-1.0% to 11.6%)
|
0.11
|
0.76
|
0.60
|
0.59
|
|
Plasma IL-6
|
17.4% (-6.7% to 47.9%)
|
0.18
|
-2.9% (-19.0% to 16.4%)
|
0.75
|
0.21
|
0.38
|
0.40
|
|
Clara cell protein
|
1.6% (-10.8% to 15.8%)
|
0.82
|
-0.27% (-11.7% to 12.7%)
|
0.97
|
0.90
|
0.91
|
0.80
|
|
Blood leukocyte counts
|
1.3% (-2.0% to 4.6%)
|
0.44
|
2.5% (-1.1% to 6.0%)
|
0.19
|
0.75
|
0.97
|
0.71
|
|
Blood neutrophil counts
|
4.6% (0.48% to 8.7%)
|
0.04
|
2.4% (-2.3% to 7.2%)
|
0.32
|
0.36
|
0.35
|
0.20
|
|
Percentage blood neutrophils
|
3.9% (1.5% to 6.2%)
|
0.003
|
0.22% (-1.8% to 2.2%)
|
0.83
|
0.004
|
0.02
|
0.01
|
- Analysis adjusted for temperature, relative humidity and heart rate
- *p-value for the interaction between pre/post-cycling measurements and exposure scenario (road test or clean room)
-
†p-value for the interaction between pre/post-cycling measurements and UFP concentrations
-
‡p-value for the interaction between pre/post-cycling measurements and PM2.5 concentrations
