Table 3 Comparison of concentrations with sensitising effects in human (HRIPT) or in mice (LLNA) to the estimated concentrations of application in products of daily use

CMI/MI

12.5 ppm [26](challenge conc. 12.5 ppm)

75 ppm (EC₃) [27]

≤ 60 ppm

2.5 - 7.5 ppm (15 ppm^a)

Glutardialdehyde

5% [28](challenge conc. 0.5%)

0.1% (EC₃) [29]

0.01 - 0.5%

≤ 0.1% (0.1%^a)

Formaldehyde

1% [28](challenge conc. 1%)

0.35% (EC₃) [30]

≤ 0.05%

≤ 0.2% (0.2%^a)

≤ 0.1%

Bronopol

5% [28](challenge conc. 2.5%)

0.0011 - 0.035%

0.01 - 0.1% (0.1%^a)

0.0011 - 0.035%

Chloroacetamide

0.5% [31](challenge conc. 0.5%)

0.1 - 0.3%

≤ 0.3% (0.3%^a)

0.1 - 0.3%