Consumer exposure to biocides - identification of relevant sources and evaluation of possible health effects

Table 4 MOE based on aggregate exposure in adults (total of all scenarios)

active substance	MOE
	Inhalation ¹	Dermal ¹	Oral ¹	Total ^{1, 2}
2-Propanol	1.8	0.26		0.26
Alkyl dimethyl benzyl ammonium chlorides (QAC)	33	0.24	25000	0.59
Sodium hypochlorite	5.2	0.040	18	0.040
Sodium dichloroisocyanurate	1.9e+10	8.7	18637	8.7
Trichloroisocyanuric acid	4122	8.4	16578	8.4
Hydrogen peroxide	0.0052	0.20	1950	0.19
Triclosan	298	31	2273	9.6
Formaldehyde	0.018	5.3	176	2.9
Glutardialdehyde	0.0043	8.3	15903	0.49
Benzoic acid	80	57	50000	57
CMI/MI	0.24	2.7	22200	1.3
1,2-Benzisothiazolin-3-one	144	2.6	66954	2.6
Bronopol	45	10	9827	4.9
2-Phenoxyethanol	4.7	21	7617	2.6
Chloroacetamide	2.3	7.7	3174	1.4
Icaridin	121	14		12
Prallethrin	6.7	761		49
Chlorpyrifos	0.058	2.3		0.011
Dichlorvos	0.00086	4.2		0.0057
Phoxim	6.4	0.27		0.20

CMI/MI = mixture of 5-chloro-2-methyl-2H-isothiazolin-3-one and 2-methyl-2H-isothiazolin-3-one
1 = value is an aggregate value of different scenarios (max 24 of 50) compared to respective NOAEL (inhalativ, dermal, oral)
2 = each scenario is limited to maximal amount used and then all scenarios are summed up. After that the value has been compared to the oral NOAEL

ISSN: 1476-069X