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Table 3 Statistical p-values for the interaction between pollutants and SNPs from MTP model using family-wise error rate and step-down max T method *

From: Effect modification of air pollution on Urinary 8-Hydroxy-2'-Deoxyguanosine by genotypes: an application of the multiple testing procedure to identify significant SNP interactions

SNP

OC

SO4 2-

O3

CAT (C/T) rs480575

0.770

1.000

1.000

CAT(A/G) rs1001179

0.770

0.825

0.749

CAT(G/A) rs2284367

0.037

0.771

0.531

CAT (A/G) rs2300181

0.131

0.976

1.00

GC (C/A) rs2282679

0.025

1.000

0.999

GC (T/C) rs1155563

0.027

1.000

0.999

GCLC (C/T) rs17883901

0.896

1.000

0.999

GCLM (A/G) rs2301022

0.745

1.000

1.000

GCLM (A/G) rs3170633

0.368

0.995

1.000

HFE (G/T) rs1799945

0.997

0.995

1.000

HFE (G/A) rs1800562

0.417

1.000

1.000

HMOX (A/T) rs2071746

0.368

0.995

1.000

HMOX (C/G) rs2071747

0.177

0.732

0.999

HMOX (G/A) rs2071749

0.770

1.000

1.000

HMOX (C/G) rs5995098

0.177

1.000

1.000

GSTP1 (A/G) rs1695

0.997

0.995

1.000

GSTP1 (C/T) rs1799811

0.997

0.091

0.994

GSTT1

0.177

0.965

1.000

GSTM1

0.037

0.984

1.000

HMOX-1

0.758

1.000

1.000

  1. * using 24-, 20- and 18-day moving averages of OC, SO4 2- and maximal 1-hour O3, respectively.