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Table 3 Statistical p-values for the interaction between pollutants and SNPs from MTP model using family-wise error rate and step-down max T method *

From: Effect modification of air pollution on Urinary 8-Hydroxy-2'-Deoxyguanosine by genotypes: an application of the multiple testing procedure to identify significant SNP interactions

SNP OC SO4 2- O3
CAT (C/T) rs480575 0.770 1.000 1.000
CAT(A/G) rs1001179 0.770 0.825 0.749
CAT(G/A) rs2284367 0.037 0.771 0.531
CAT (A/G) rs2300181 0.131 0.976 1.00
GC (C/A) rs2282679 0.025 1.000 0.999
GC (T/C) rs1155563 0.027 1.000 0.999
GCLC (C/T) rs17883901 0.896 1.000 0.999
GCLM (A/G) rs2301022 0.745 1.000 1.000
GCLM (A/G) rs3170633 0.368 0.995 1.000
HFE (G/T) rs1799945 0.997 0.995 1.000
HFE (G/A) rs1800562 0.417 1.000 1.000
HMOX (A/T) rs2071746 0.368 0.995 1.000
HMOX (C/G) rs2071747 0.177 0.732 0.999
HMOX (G/A) rs2071749 0.770 1.000 1.000
HMOX (C/G) rs5995098 0.177 1.000 1.000
GSTP1 (A/G) rs1695 0.997 0.995 1.000
GSTP1 (C/T) rs1799811 0.997 0.091 0.994
GSTT1 0.177 0.965 1.000
GSTM1 0.037 0.984 1.000
HMOX-1 0.758 1.000 1.000
  1. * using 24-, 20- and 18-day moving averages of OC, SO4 2- and maximal 1-hour O3, respectively.