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Table 3 Results from weighted logistic regression models with the outcome neural tube defects (n = 112)

From: Arsenic is associated with reduced effect of folic acid in myelomeningocele prevention: a case control study in Bangladesh

Variable

Main effects model

Interaction model

 

β

OR (95% CI) 1

pValue

β

OR (95% CI) 1

p Value

Ln-water As

0.0278

1.03 (0.96, 1.11)

0.45

−0.3190

-

-

Periconceptional folic acid use2

−1.2029

0.300 (0.19, 0.47)

<0.0001

1.7280

-

-

Home birth3

0.9224

2.51 (1.61, 3.92)

<0.0001

1.0047

2.73 (1.72, 4.32)

<0.0001

Mother’s age in years

0.1649

1.18 (1.10, 1.26)

<0.0001

0.1573

1.17 (1.09, 1.26)

<0.0001

Father’s age in years

−0.0607

0.94 (0.89, 1.00)

0.05

−0.0416

0.96 (0.90, 1.01)

0.17

Child sex4

0.9152

2.50 (1.56, 3.99)

0.0001

0.7986

2.22 (1.38, 3.59)

0.001

Child age in months

−0.1305

0.88 (0.84, 0.92)

<0.0001

−0.1337

0.88 (0.94, 0.91)

<0.0001

Ln-water As*prenatal folic acid use

   

0.4636

-

<0.0001

  1. 1OR indicates odds of being a CASE.
  2. 2Reported use = 1, No reported use = 0.
  3. 3Home birth = 1, Clinic or Hospital birth = 0.
  4. 4Male = 1, Female = 0.
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Environmental Health

ISSN: 1476-069X