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Table 4 Incidence rate ratios for ABC scores among DD and ASD in relation to dust phthalate concentrations, CHARGE study

From: Phthalate concentrations in house dust in relation to autism spectrum disorder and developmental delay in the CHildhood Autism Risks from Genetics and the Environment (CHARGE) study

 

Hyperactivity/ Impulsivity

Inattention

 

IRR

95% CI

IRR

95% CI

Boys and Girls

    

Dimethyl phthalate

0.97

[0.82; 1.15]

1.02

[0.91; 1.14]

Diethyl phthalate

1.16

[0.95; 1.42]

1.06

[0.95; 1.19]

Dibutyl phthalate

1.35

[0.98; 1.85]

1.13

[0.91; 1.39]

Butylbenzyl phthalate

1.02

[0.86; 1.21]

1.03

[0.90; 1.18]

Di(2-ethylhexyl) phthalate

0.80

[0.61; 1.06]

1.03

[0.88; 1.20]

Boys only

    

Dimethyl phthalate

0.98

[0.82; 1.17]

1.01

[0.90; 1.12]

Diethyl phthalate

1.25

[1.02; 1.54]

1.13

[1.03; 1.24]

Dibutyl phthalate

1.63

[1.22; 2.19]

1.25

[0.96; 1.62]

Butylbenzyl phthalate

1.10

[0.88; 1.37]

1.03

[0.91; 1.17]

Di(2-ethylhexyl) phthalate

0.94

[0.68; 1.30]

1.15

[0.95; 1.39]

  1. Analyses adjusted for child age at assessment, child gender and race, maternal education and date of dust collection
  2. Associations between phthalates and ABC subscales are not reported among TD because of the high prevalence of 0 score in this group (~50 %)
  3. IRR Incidence rate ratio