Skip to main content

Table 4 Structural equation models for the association between antibodies and latent joint PFAS concentrations. Shown are models for latent PFAS at age 5 years (row 1), latent PFAS at age 7 years (row 2), and latent childhood PFAS (row 3). % Change indicates the percentages change in antibody concentration for a 2-fold PFAS concentration. All models were adjusted for the covariates gender, age, and booster type

From: Structural equation modeling of immunotoxicity associated with exposure to perfluorinated alkylates

   Diphtheria Tetanus   Joint
Model N % Change 95 % CI % Change 95 % CI P a % Change 95 % CI
Additional file 1: Model 3         
PFAS at age 5b 448 −44.8 −65.8, −11.0 −55.9 −73.6, −26.2 0.40 −50.0 −67.2, 23.8
PFAS at age 7c 448 −57.5 −77.1, −21.2 −49.8 −74.1, −2.8 0.64 −54.4 −73.3, −22.0
Additional file 1: Model 5d         
PFAS childhood 448 −57.5 −76.9, −21.8 −60.1 −79.3, −22.8 0.64 −55.5 −73.4, −25.5
  1. aP-value for the test of same effect on the two antibodies
  2. bGoodness-of-fit (same effect model,): χ2-test P: 0.20, RMSEA: 0.03, CFI: 0.99, SRMR: 0.02
  3. cGoodness-of-fit (same effect model): χ2-test P: 0.41, RMSEA: 0.01, CFI: 0.99, SRMR: 0.02
  4. dGoodness-of-fit (same effect model): χ2-test P: 0.24, RMSEA: 0.02, CFI: 0.99, SRMR: 0.02