Environmental Health

Table 2 Fecundability ratios according to plasma PFOS and PFOA

From: Perfluoroalkyl acids and time to pregnancy revisited: An update from the Danish National Birth Cohort

		Sample 1			Sample 2			Pooled analysis
		Crude FR	Adjusted^a FR	95 % CI	Crude FR	Adjusted^a FR	95 % CI	Crude FR	Adjusted^b FR	95 % CI
PFOS
	Q1	1.00	1.00		1.00	1.00		1.00	1.00
	Q2	1.06	1.08	0.81 - 1.44	0.79	0.79	0.66 - 0.95	0.85	0.87	0.75 - 1.02
	Q3	0.99	0.99	0.73 - 1.34	0.80	0.78	0.65 - 0 .95	0.84	0.85	0.72 - 0.99
	Q4	0.91	0.99	0.74 - 1.33	0.75	0.78	0.65 - 0.94	0.79	0.85	0.72 – 0.99
	Log	0.94	0.96	0.75 – 1.24	0.74	0.76	0.62 – 0.92	0.79	0.83	0.72 – 0.97
PFOA
	Q1	1.00	1.00		1.00	1.00		1.00	1.00
	Q2	0.91	0.92	0.69 - 1.22	0.75	0.78	0.65 - 0.94	0.79	0.81	0.70 - 0.95
	Q3	0.90	0.94	0.71 - 1.26	0.80	0.83	0.69 - 1.00	0.82	0.86	0.74 - 1.01
	Q4	0.74	0.86	0.63 - 1.19	0.69	0.74	0.60 - 0.90	0.70	0.78	0.66 - 0.92
	Log	0.75	0.89	0.68 – 1.15	0.69	0.72	0.61 – 0.85	0.70	0.77	0.67 – 0.89

^aAdjusted for age, socio-economic status, body mass index, and parity. ^bAdditionally adjusted for sample
Abbreviations: Perfluorooctane sulfonate (PFOS), perfluorooctanoate (PFOA), quartile (Q), log-transformed continuous exposure levels (Log), fecundability ratio (FR), 95 % confidence interval (95 % CI)
The fecundability ratio denotes the probability of conceiving in a given interval in a group of women with higher exposure compared to the reference group, conditionally on not having conceived in the previous period

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ISSN: 1476-069X

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