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Table 4 Pharmacokinetic model-based estimate for cumulative MeHg exposure by diagnostic group

From: Prenatal mercury exposure, autism, and developmental delay, using pharmacokinetic combination of newborn blood concentrations and questionnaire data: a case control study

 

Area under the curve (ppb)

 

2nd and 3rd trimesters

Gestational period

 

ASD

DD/AtD

TD

ASD

DD/AtD

TD

Number

153

32

53

153

32

53

Method 1a

      

Median

133

140

140

219

262

203

95th %

428

360

408

693

580

680

Range

0 - 545

0 - 378

0 - 443

0 - 1231

0 - 654

0 - 702

Method 2b

      

Median

144

149

152

241

286

218

95th %

438

388

407

732

680

688

Range

0 - 1395

0 - 487

0 - 523

0 - 1703

0 - 713

0 - 800

  1. aMethod 1 converts individual maternal body weight to volume of blood based on weight during each time period
  2. bMethod 2 converts individual maternal body weight to volume of blood based on weight gain during pregnancy