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Table 2 Pre-exposure values of biological endpoints

From: Repeated measures of inflammation, blood pressure, and heart rate variability associated with traffic exposures in healthy adults

   SF GSP GWB P-value
  Subjects (n) Mean (range) Mean (range) Mean (range)  
Respiratory measurements  
eNO (ppb) 19 22 (8–66) 24 (9–61) 19 (9–50) 0.14
FVC (L) 18 4.6 (3.3-6.8) 4.7 (3.2-6.6) 4.6 (3.3-6.5) 0.96
FEV1 (L) 18 3.8 (2.7-6.1) 3.7 (2.6-5.7) 3.8 (2.7-5.9) 0.61
FEV1/FVC 18 0.8 (0.6-0.9) 0.9 (0.6-1.0) 0.8 (0.6-1.0) 0.44
Inflammatory measurements
CRP (ng/mL) 17 30.1 (1.3-93.9) 31.6 (0.9-149.3) 53.2 (6.3-225.3) 0.01*
SAA (ng/mL) 16 32.1 (6.1-93.9) 29.8 (3.9-88.3) 66.5 (9.4-355.1) 0.08
sICAM (ng/mL) 17 4.4 (2.2-8.1) 4.5 (1.7-7.3) 5.5 (2.5-8.8) 0.01*
IL-1β (pg/mL) 21 3.7 (0.4-13.9) 3.6 (0.2-17.7) 3.0 (0.2-25.9) 0.86
IL-8 (pg/mL) 21 3.3 (0.8-15.3) 2.4 (0.0-6.7) 2.0 (0.8-5.0) 0.13
Cortisol (ng/mL) 10 0.4 (0.1-0.8) 0.4 (0.2-0.6) 0.3 (0.1-0.6) 0.21
Blood pressure measurements  
SBP (mmHg) 18 126 (106–166) 124 (95–162) 129 (109–155) 0.27
DBP (mmHg) 18 82 (66–103) 82 (64–97) 79 (56–99) 0.21
PP (mmHg) 18 43 (23–70) 41 (19–65) 46 (15–63) 0.14
MAP (mmHg) 18 97 (81–124) 96 (76–119) 96 (78–118) 0.91
Heart rate variability measurements
SDNN (ms) 18 77 (34–186) 72 (28–164) 75 (43–106) 0.81
rMSSD (ms) 18 41 (15–118) 43 (13–161) 48 (18–94) 0.57
HF (ms2) 18 1048 (23–6822) 1054 (20–7261) 1106 (52–4574) 0.99
LF (ms2) 18 1651 (407–4835) 2483 (110–13518) 1599 (250–4186) 0.23
LF:HF 18 5.0 (0.5-20.6) 4.9 (0.2-13.1) 3.0 (0.3-6.6) 0.10
Heart rate (BPM) 18 77.8 (58.9-94.9) 78.9 (60.4-118.1) 78.7 (62.2-128.0) 0.94
  1. SF Sterling Forest, GSP Garden State Parkway, GWB George Washington Bridge. Statistically significant differences in pre-exposure values were assessed using repeated-measures ANOVA. *p-value < 0.05
  2. Pre-exposure values expressed as mean (range) at each location